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Department of Pathology

 

Cancer arises when cells lose the ability to die following injury, begin to divide uncontrollably and invade other tissues. Cancer cells spread by direct growth into adjacent tissue or by implantation into distant sites, a process called metastasis and whereby cancer cells are transported through the bloodstream or lymphatic system to distant sites. The unregulated growth that characterizes cancer is caused by damage to DNA, resulting in mutations to genes that encode proteins controlling cell division. These mutations can be caused by chemicals or physical agents called carcinogens, by close exposure to radioactive materials, or by certain viruses that can insert their DNA into the human genome. Mutations may occur spontaneously, or may be passed down from one generation to the next in the germ lines.

Researchers within this thematic investigate common human tumours such as breast cancer, lymphoma and brain tumours in order to try to understand the genetic mutations resulting in these disorders and, hopefully, identify points of attack by new therapies.


People specializing in this area

Research Group Leaders

Dr Paolo  D'Avino
University Senior Lecturer
Division of Cellular and Molecular Pathology
+44 (0)1223 333712
Professor Ming-Qing  Du
Professor of Oncological Pathology
Division of Cellular and Molecular Pathology
+44 (0)1223 767092
Anton Enright
University Lecturer and Group Leader- Division of Cellular and Molecular Pathology
Academic Lead - Cambridge Genomic Services
Staff Fellow, Director of Studies, Deputy Graduate Tutor - Trinity Hall
+44 1223 339871
Reader in Cellular and Molecular Biology
Co-Director of CRUK Cambridge Centre Postgraduate Training Programme (MRes/PhD)
Fellow & Director of Studies for Pathology and Genetics, Clare College
Graduate Admission Tutor, Clare College
+44 (0)1223 333722
Dr Bidesh  Mahata
Research Group Leader (CRUK Career Development Fellow)
Division of Immunology
+44 (0) 01223 764518
Dr Rahul  Roychoudhuri
University Senior Lecturer, Division of Immunology
Theme Lead in Infection and Immunity
Director of Studies in Pathology, St Catharine's College
Dr Suzanne D Turner
Reader in Cellular and Molecular Tumour Biology
Division of Cellular and Molecular Pathology
+44 (0) 1223 762655
Professor Christine  Watson
Professor of Cell and Cancer Biology
Division of Cellular and Molecular Pathology
+44 (0)1223 333725

Cellular and Molecular Pathology

Dr Paolo  D'Avino
University Senior Lecturer
Division of Cellular and Molecular Pathology
+44 (0)1223 333712
Professor Ming-Qing  Du
Professor of Oncological Pathology
Division of Cellular and Molecular Pathology
+44 (0)1223 767092
Anton Enright
University Lecturer and Group Leader- Division of Cellular and Molecular Pathology
Academic Lead - Cambridge Genomic Services
Staff Fellow, Director of Studies, Deputy Graduate Tutor - Trinity Hall
+44 1223 339871
Reader in Cellular and Molecular Biology
Co-Director of CRUK Cambridge Centre Postgraduate Training Programme (MRes/PhD)
Fellow & Director of Studies for Pathology and Genetics, Clare College
Graduate Admission Tutor, Clare College
+44 (0)1223 333722
Dr Suzanne D Turner
Reader in Cellular and Molecular Tumour Biology
Division of Cellular and Molecular Pathology
+44 (0) 1223 762655
Professor Christine  Watson
Professor of Cell and Cancer Biology
Division of Cellular and Molecular Pathology
+44 (0)1223 333725

Immunology

Dr Bidesh  Mahata
Research Group Leader (CRUK Career Development Fellow)
Division of Immunology
+44 (0) 01223 764518
Dr Rahul  Roychoudhuri
University Senior Lecturer, Division of Immunology
Theme Lead in Infection and Immunity
Director of Studies in Pathology, St Catharine's College