Department of Pathology

Proteomics of cold sore virus (HSV-1) infection

Recent work from the Crump and Graham groups in the Division of Virology illuminate how herpes simplex virus remodels the protein composition of infected cells.

How herpes viruses put on their protective coat

Recent work from the Graham and Crump groups in the Division of Virology have revealed the unexpected mechanism by which new herpesvirus particles obtain their membrane coats when assembling inside infected cells.

An autonomous oscillation times and executes centriole biogenesis

Cells must accurately grow centrioles to the correct length at the correct time in the cell cycle in order to maintain normal physiology. Michael Boemo, who recently joined the department as a research group leader, collaborated with the Raff lab (Dunn School of Pathology, University of Oxford) to show that centriole growth is controlled by oscillating levels of the Polo-like kinase Plk4.

Welcome to Dr Rahul Roychoudhuri

We are delighted to welcome Dr Rahul Roychoudhuri to the Department of Pathology from June 1st, 2020. Rahul will join the Division of Immunology as Senior Lecturer. His research focus will be on the regulation of immune responses, especially as controlled by regulatory T cells.

Studies of pathogen-host interactions frequently help to understand cell biology.

A new collaborative paper from Richard Hayward (Pathology), Jenny Gallop (Gurdon Institute) and Astra Zeneca published in the Journal of Cell Biology reveals parallels between the mechanism of Chlamydia trachomatis cell entry and how cells construct filopodia, fundamental cytoskeletal structures important for motility and development.

Distinct polymorphisms in MHC class I molecules govern their susceptibility to peptide editing by TAPBPR

MHC class I molecules play a critical role in immunosurveillance by presenting antigenic peptides to CD8+ T lymphocytes. Research in the Boyle group in the Department of Pathology focuses on understanding how peptides are selected on MHC class I for immune recognition.

Path mentors

Members of our Department are available to all staff to provide advice and guidance in specific areas, including applying for funding, career progression and teaching.

Rosetrees Trust funding malaria research

Group Leader Dr Andrew Blagborough has been awarded funding from the Rosetrees Trust for his project “Targeting the function of Plasmodium Protein Disulphide Isomerase to Prevent Malarial Transmission.”

24 Portraits: Recovering and Reimagining Women's Labour

Emma Copley has created a site-specific installation of painted portraits of women who currently work in all areas of the Department of Pathology including laboratory managers, academics, cleaners, lecturers, administrators and technicians.

Equality, Diversity and Wellbeing website

Equality, Diversity and Wellbeing Portal

Our new Equality, Diversity and Wellbeing portal has been launched.

Athena SWAN

The Department has achieved an Athena SWAN bronze award.

Ita Askonas Bursaries

The Ita Askonas Bursaries are intended to allow postdoctoral researchers in the fields of infection and immunology to pursue specific research projects or networking opportunities at another institution, either to further their current research project, or to generate new areas of research. Details for the next round of applications will be available soon.

COVID-19

Advice for staff and students at the University and Colleges on novel coronavirus (COVID-19). The University is continually monitoring latest Public Health England and government advice about the virus.

Safe Space Information

In collaboration with the University Safe Space team, the department has generated a Return to the Workplace document that outlines the current social distancing measures which are in place to protect the safety and welfare of you and others. This document is updated frequently as guidance changes.