skip to content

Department of Pathology

 
Read more at: Flexibility in viral translation initiation revealed in enteroviruses

Flexibility in viral translation initiation revealed in enteroviruses

11 February 2026

Researchers led by Dr Valeria Lulla have uncovered new insights into how enteroviruses regulate protein production, revealing unexpected flexibility in viral translation initiation. This study was carried out in collaboration with the Firth and Graham Groups in Virology, the Deane lab at CIMR, and the Zilbauer lab at...


Read more at: Breaking Down Barriers: Improving CAR T-Cell Therapy for Colorectal Cancer

Breaking Down Barriers: Improving CAR T-Cell Therapy for Colorectal Cancer

30 January 2026

New Advances in CAR T-Cell Therapy for Colorectal Cancer Researchers in  the Mahata Group  , in collaboration with Prof Sir David Klenerman and colleagues , have uncovered a key reason why anti-CEACAM5 CAR T-cell therapies — a promising form of immunotherapy — have so far struggled to treat colorectal cancer (CRC), and...


Read more at: Reading the Signals: How Malaria Parasites Respond to Host Stress

Reading the Signals: How Malaria Parasites Respond to Host Stress

30 January 2026

Understanding how malaria parasites respond to stress within the human host is central to explaining both disease severity and transmission. In a recent study led by Professor Catherine Merrick , researchers uncovered a previously unrecognised mechanism by which Plasmodium parasites sense and respond to changes in host...


Read more at: The Macrophage Maneuver: Eddie’s Method for Silencing All Resistance

The Macrophage Maneuver: Eddie’s Method for Silencing All Resistance

5 December 2025

In a recent study exploring how Toxoplasma gondii seizes control of immune cells through early, stealthy suppression, researchers uncovered a strategy so cunning a movie villain could have devised it. And in Betty Chung's household, one charismatic orange feline— Eddie, Lord of Fluff and Shadows —appears to have taken...


Read more at: Specialist in stealthy cell takeover and corporate-style infiltration — now hiring macrophage contacts.

Specialist in stealthy cell takeover and corporate-style infiltration — now hiring macrophage contacts.

3 December 2025

A recent study published in Nature Communications by Professor Betty Chung uncovers an unexpected early-stage strategy used by Salmonella enterica to manipulate the host immune system. Researchers found that immediately upon contact with a macrophage, the bacterium’s injectisome triggers rapid reprogramming of the host’s...


Read more at: Same Instructions, Different Results: What ribosomal frameshifting can learn from Leg Day at the gym

Same Instructions, Different Results: What ribosomal frameshifting can learn from Leg Day at the gym

28 November 2025

Introduction If you’ve ever watched two people tackle the same leg-day routine at the gym — maybe a guy and a girl doing identical sets of squats, lunges, and step-ups — you know that the results are rarely carbon copies. One person glides through the reps with perfect form while the other adapts, compensates, or only...


Read more at: New study links faulty B cell development to Alzheimer’s disease – independent of age and lifestyle

New study links faulty B cell development to Alzheimer’s disease – independent of age and lifestyle

26 November 2025

An extensive new study has identified a specific fault in the immune system of people with Alzheimer’s disease, pointing to a previously underexplored avenue for understanding – and potentially treating – the condition. Researchers used a “systems immunology” approach to analyse blood samples from 184 people with Alzheimer...


Read more at: Basics of women's health revealed with the help of mini placentas and ovaries

Basics of women's health revealed with the help of mini placentas and ovaries

25 September 2025

Lab-made organoids that mimic reproductive tissues could point to treatments for common conditions such as pre-eclampsia and endometriosis. In 2017, Ashley Moffett , a reproductive immunologist, walked to the pharmacy near her laboratory at the University of Cambridge in the UK to buy a pregnancy test. But it wasn’t for...


Read more at: There is no evidence that vaccines drive any kind of process that results in cancer

There is no evidence that vaccines drive any kind of process that results in cancer

8 September 2025

Professor Brian Ferguson has firmly rejected claims made at a Reform UK health conference suggesting Covid-19 vaccines could be linked to cancers in the royal family. Dr Aseem Malhotra, a cardiologist and guest speaker at the “Make Britain Healthy Again” event in Birmingham, alleged that mRNA vaccines may have been a...


Read more at: New protein-based tools boost fight against Oropouche virus

New protein-based tools boost fight against Oropouche virus

20 August 2025

Researcher Professor Stephen Graham has helped develop a suite of powerful protein-based tools that could transform the detection, study, and treatment of the Oropouche virus (OROV), a neglected tropical pathogen now linked to severe outbreaks and even fatalities. The study, published in EMBO Molecular Medicine , reports...