Dr Stephen Sitha and his group focus on using cutting-edge computational and mathematical tools to understand the pathogenesis and aetiology of cancer.
Department of Pathology
My research is focused on using cutting edge computational and mathematical tools to understand the pathogenesis and aetiology of cancer, in particular squamous cell carcinoma. As a dermatologist and clinical pharmacologist I am ultimately driven by the need to translate the findings of fundamental scientific research into clinically relevant outcomes.
Smith SP, Scarpini CG, Groves IJ, Odle RI, Coleman N
Identification of host transcriptional networks showing concentration-dependent regulation by HPV16 E6 and E7 proteins in basal cervical squamous epithelial cells.
Scientific Reports Jul 2016; 6:29832. https://doi.org/10.1038/srep29832
Pellagatti A, Steeples V, Armstrong RN, Sharma E, Repapi E, Singh S, Sanchi A, Radujkovic A, Horn P, Dolatshad H, Roy S, Lockstone H, Taylor S, Giagounidis A, Vyas P, Schuh A, Hamblin A, Papaemmanuil E, Killick S, Malcovati L, Gavin A-C, Ho AD, Luft T, Hellström-Lindberg E, Cazzola M, Smith CWJ, Smith SP, and Boultwood J
Impact of spliceosome mutations on RNA splicing in myelodysplasia: dysregulated genes/pathways and clinical associations.
Blood 2018 Jun 21. pii: blood-2018-04-843771. https://doi.org/10.1182/blood-2018-04-843771
Department of Pathology
University of Cambridge
Tennis Court Road
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CB2 1QP
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