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Department of Pathology

 

Research

My research is focused on using cutting edge computational and mathematical tools to understand the pathogenesis and aetiology of cancer, in particular squamous cell carcinoma. As a dermatologist and clinical pharmacologist I am ultimately driven by the need to translate the findings of fundamental scientific research into clinically relevant outcomes.

Publications

Key publications: 

Smith SP, Scarpini CG, Groves IJ, Odle RI, Coleman N
Identification of host transcriptional networks showing concentration-dependent regulation by HPV16 E6 and E7 proteins in basal cervical squamous epithelial cells.
Scientific Reports Jul 2016; 6:29832. https://doi.org/10.1038/srep29832

Pellagatti A, Steeples V, Armstrong RN, Sharma E, Repapi E, Singh S, Sanchi A, Radujkovic A, Horn P, Dolatshad H, Roy S, Lockstone H, Taylor S, Giagounidis A, Vyas P, Schuh A, Hamblin A, Papaemmanuil E, Killick S, Malcovati L, Gavin A-C, Ho AD, Luft T, Hellström-Lindberg E, Cazzola M, Smith CWJ, Smith SP, and Boultwood J
Impact of spliceosome mutations on RNA splicing in myelodysplasia: dysregulated genes/pathways and clinical associations.
Blood 2018 Jun 21. pii: blood-2018-04-843771. https://doi.org/10.1182/blood-2018-04-843771

Clinical Research Fellow
Division of Cellular Molecular Pathology
Dr Stephen  Smith

Contact Details

Not available for consultancy