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Department of Pathology

 

Alberto Giaretta has been a full-time researcher in the field of Systems Biology since 2013. He received a high school technical diploma in Electronics and Telecommunications in 2006 from ITI A. Meucci, a Bachelor's degree in Biomedical Engineering from the University of Padova, a Master's degree in Bioengineering from the University of Padova. He received a Ph.D. in Information Engineering, Bioengineering stream, from the University of Padova, Italy (in collaboration with the Elston's lab at the University of North Carolina at Chapel Hill, USA) working on modeling the Human Papillomavirus (HPV) gene regulation, modeling the interaction of Aspirin with COX-1 enzyme under both healthy and pathological conditions and modeling the gene regulation of aging in yeast. During his post-doc at the Department of Information Enginnering at the University of Padova, Italy, he focused on modeling HPV gene networks, PBPK/PD modeling of cardio-aspirin, systems pharmacology of Doxorubicin in multiple myeloma cells, developing novel mathematical frameworks to model gene networks, mouse and human papillomavirus molecular biology and developing mathematical methods for parameter estimation of hybrid stochastic systems. In 2021 he won a Marie Skłodowska-Curie individual fellowship from the European Commission within the call H2020-MSCA-IF-EF-2020-ST.

His main research topics are: systems virology of Human Papillomavirus, systems biology and biophysics of epithelial tissue, systems biology of single cell gene networks and signalling patwhays, mathematical frameworks for modeling gene networks,  biology of Human and mouse papillomavirus, methods for stochastic systems biology, estimation methods for hybrid stochastic systems, systems pharmacology of cardio-aspirin and doxorubicin.

Alberto is currently a Marie Skłodowska-Curie fellow at the University of Cambridge, division of virology, in Doorbar's lab at the Department of Pathology. Alberto is also a member of Trinity College, at the University of Cambridge.

Alberto's major project is entitled STEPV (Spatio-Temporal stochastic modEls for phenotype and gene regulation by the human PapillomaVirus), a project funded by the European Commission through the "Marie Sklodowska-Curie Actions"- Individual Fellowship (H2020-MSCA-IF-EF-2020-ST)", within Horizon 2020 (Project N. 101033459).

Alberto's major collaborators related to STEPV are with: Professor Ben Simons at the Gurdon Institute in Cambridge; Professor Gianluigi Pillonetto at the University of Padova, Italy; Professor Timothy Elston at the University of North Carolina in Chapel Hill.

STEPV aims at performing novel biological investigations regarding the homeostasis of the epithelium subject to HPV infection and antiviral drug administration and at developing novel spatio-temporal mathematical modeling frameworks in order to describe HPVs phenotype control and its connection with gene expression.

For further information, please visit the following links: Linkedin.

Marie Curie Individual Research Fellow
Division of Virology
Not available for consultancy

Affiliations