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Department of Pathology

 

Genomics is the study of an organism's entire genome. A major branch of genomics is concerned with sequencing the genomes of various organisms. It has been used to sequence the entire genome of the mouse, Xenopus frog and even humans. Such knowledge of complete genomes has created the possibility for functional genomics, the study of the result of patterns of gene expression under various conditions. Expression of thousands of genes can be measured simultaneously using microarrays and analysed by sophisticated computational tools. For example, microarrays can be used to identify disease genes by comparing gene expression in diseased and normal cells and many researchers within the Department are using genomics for just that reason.


People specializing in this area

Research Group Leaders

Professor Nabeel  Affara
Professor of Molecular Genetics and Genomics
Division of Cellular and Molecular Pathology
+44 (0)1223 333700
Professor Nick  Coleman
Professor of Molecular Pathology
Head of the Division of Cellular and Molecular Pathology
+44 (0)1223 766422
Dr Paul  Edwards
Reader in Cancer Biology (retired)
Division of Cellular and Molecular Pathology
Dr Bidesh  Mahata
Research Group Leader (CRUK Career Development Fellow)
Division of Immunology
+44 (0) 01223 764518

Cellular and Molecular Pathology

Professor Nabeel  Affara
Professor of Molecular Genetics and Genomics
Division of Cellular and Molecular Pathology
+44 (0)1223 333700
Professor Nick  Coleman
Professor of Molecular Pathology
Head of the Division of Cellular and Molecular Pathology
+44 (0)1223 766422

Immunology

Dr Bidesh  Mahata
Research Group Leader (CRUK Career Development Fellow)
Division of Immunology
+44 (0) 01223 764518