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Department of Pathology

 
Read more at: How do viruses infect neuronal cells?

How do viruses infect neuronal cells?

28 July 2023

The Lulla research group has published a study on hotspots in neurotropic human astroviruses. This study, led by Hashim Ali, has found "hotspots" in genomes of neurotropic human astroviruses that allow them to infect neurons. It describes a molecular toolkit for studying non-classical human astroviruses, a family of...


Read more at: Career advice: Strategic career building during your PhD

Career advice: Strategic career building during your PhD

28 July 2023

PhD training can be incredibly versatile and can open up many career paths. A structured approach empowers PhD researchers to maximize their opportunities, positioning them for long-term success in the various career options within and beyond academia. Professor Adrian Liston and Lydia Makaoff have put together a timeline...


Read more at: Would a time traveller start a pandemic?

Would a time traveller start a pandemic?

7 June 2023

Would a time traveller start a pandemic? Or would they die of diseases their immune system couldn't protect against? Gary wrote to ask the Naked Scientist's podcast : "Suppose I build a time machine that can transport me one decade, century or millennium into the past or future. Would I, with all my typical 2023 bacteria...


Read more at: A new study highlights Salmonella's effective cell invasion mechanism

A new study highlights Salmonella's effective cell invasion mechanism

31 May 2023

A new study of Salmonella bacteria finds the pathogen surprisingly restricts its uptake if a cell is already infected. This self-limiting mechanism is due to effector-driven activation of N-WASP—the host actin regulator. Salmonella causes various diseases in both humans and animals. Typically ingested through contaminated...


Read more at: A review of common cancer tests calls for new biomarkers

A review of common cancer tests calls for new biomarkers

31 May 2023

A review in Nature Reviews Urology reveals common blood test markers used to diagnose cancers affecting young people have a high rate of false positives. The Murray and Coleman groups, with Senior Research Associate Dr Cinzia Scarpini, have just published a review of an article assessing current blood test markers used to...


Read more at: New study comprehensively maps placental development in unprecedented detail

New study comprehensively maps placental development in unprecedented detail

4 April 2023

Researchers have mapped placental development from start to finish in a new study published in Nature. Using single-cell, spatial-omics, and multi-omics approaches creates an in-depth, high-resolution picture of how the placenta develops and communicates with the uterus. The research team, including Professor Ashley...


Read more at: Professor Elizabeth Sollieux wins prestigious Pilkington Prize

Professor Elizabeth Sollieux wins prestigious Pilkington Prize

9 March 2023

pilkington_23_soilleux_crop.jpg Professor Liz Soilleux has contributed tirelessly to pre-clinical pathology teaching over many years. Before the COVID-19 pandemic, she updated the Biology of Disease histopathology practical classes to reflect current diagnostic practice. She had undertaken professional development in...


Read more at: McGovern Lab wins European Research Council Consolidator Grants

McGovern Lab wins European Research Council Consolidator Grants

2 February 2023

Dr Naomi McGovern of the Department of Pathology and the Centre for Trophoblast Research has been awarded a European Research Council (ERC) Consolidator Grant The grant will support PMDR: Placental macrophages: Their development and role in the placenta. My team’s research focus is human placental macrophage biology. We...


Read more at: New Professor of Pathology appointed

New Professor of Pathology appointed

13 January 2023

The Department of Pathology is delighted to announce the appointment of a new Professor of Pathology, Adrian Liston FMedSci. liston_crop.jpg After an extensive search that attracted many exceptional candidates, we are delighted to have recruited Adrian Liston as our new Professor of Pathology. Professor Liston has an...


Read more at: First approved immunotherapy for melanoma triggers potent anti-tumour responses

First approved immunotherapy for melanoma triggers potent anti-tumour responses

2 December 2022

An IL-2 variant that is more tolerant of the acidic tumour environment improves immunotherapy in mice with melanoma. Researchers have created a variant of human IL-2 that can overcome challenges it experiences in the low-pH environment of tumours, boosting its ability to promote CD8 T cell and natural killer (NK) cell...