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Department of Pathology

 
Read more at: Groundbreaking study reveals Aspirin’s potential to prevent cancer metastasis by boosting immune response

Groundbreaking study reveals Aspirin’s potential to prevent cancer metastasis by boosting immune response

5 March 2025

A new study published in Nature has uncovered a novel mechanism by which aspirin inhibits cancer metastasis by strengthening the body’s immune response. Researchers at the University of Cambridge and international collaborators have demonstrated that aspirin enhances T-cell immunity by counteracting platelet-derived...


Read more at: Saving lives by tackling Malaria

Saving lives by tackling Malaria

20 February 2025

The WHO describes malaria as 'perpetuating a vicious cycle of inequity'. What are we doing to fight spread and infection? Professor Catherine Merrick comments in the latest episode of the EU's CORDIScovery podcast. Listen here>>


Read more at: Developing kinder treatments for patients with germ cell tumours

Developing kinder treatments for patients with germ cell tumours

8 January 2025

New research from the Department of Pathology, University of Cambridge and CRUK Cambridge Centre Paediatric Cancer Programme members have identified a set of microRNAs in malignant germ cell tumours (GCTs), which may provide new treatment options for patients. In this work, now published in the Molecular Oncology journal...


Read more at: Professor Ashley Moffett awarded Companion of the Order of St Michael and St George

Professor Ashley Moffett awarded Companion of the Order of St Michael and St George

7 January 2025

We are delighted to announce that Professor Ashley Moffett has been awarded Companion of the Order of St Michael and St George in the King's New Year's Honours. Professor Ashley Moffett , Professor of Reproductive Immunology at the University of Cambridge, was awarded the prestigious CMP for services to Women’s...


Read more at: DNA replication timing reveals genome-wide features of transcription and fragility

DNA replication timing reveals genome-wide features of transcription and fragility

16 December 2024

DNA replication in humans requires precise regulation to ensure accurate genome duplication and maintain genome integrity. A key indicator of this regulation is replication timing, which reflects the interplay between origin firing and fork dynamics. We present a high-resolution (1-kilobase) mathematical model that maps...


Read more at: DNA duplication revealed as key cause of testicular cancer

DNA duplication revealed as key cause of testicular cancer

5 November 2024

New insights into the genomic drivers of testicular cancer in adults have been discovered by detailed whole genome analysis of samples from the 100,000 Genomes Project. Malignant germ cell tumours (GCTs) are complex cancers that affect patients of all ages. They develop from cells that produce eggs or sperm and mainly...


Read more at: Congratulations Professor Heike Laman

Congratulations Professor Heike Laman

15 October 2024

Congratulations to Professor Heike Laman , Head of Department, on her nomination for the Research Culture Celebration 2024 , in recognition of her contributions to a positive Research Culture among all department staff. Cambridge aspires to create a positive research culture where all staff working in research, whether in...


Read more at: Finally there is hope on the horizon– excitement over pancreatic cancer jab

Finally there is hope on the horizon– excitement over pancreatic cancer jab

26 September 2024

A cancer patient in Birmingham has become the first person in Europe to sign up for a ground-breaking clinical trial for a new pancreatic cancer vaccine. Pancreatic cancer is one of the most deadly forms of cancer, and experts said that the launch of the European arm of the trial means that “hope is on the horizon”...


Read more at: Breast implants linked to cancer

Breast implants linked to cancer

25 September 2024

The human pursuit of body perfection and ideal aesthetics means we increasingly resort to cosmetic interventions to achieve our desired look. Some surveys suggest that the breast implant market is growing at 7% per year, despite women suing a breast implant manufacturer over alleged links with a rare cancer. Professor...


Read more at: Black in Cancer: I wanted to be that person for black researchers

Black in Cancer: I wanted to be that person for black researchers

20 August 2024

Black in Cancer has worked with Cancer Research UK (CRUK) to launch the Black Leaders in Cancer PhD Scholarship Programme, external to help develop the next generation of black scientists. In his first year of the CRUK-funded scholarship programme, Randy Greaves said it allowed him to realise a life-long dream. After his...