Dr Liz Hook

Medical Education

Paediatric Tumour Histopathology

Biography

I hold overall responsibilty for the organisation, delivery and examination of the Clinical Pathology Course. As well as being Senior Examiner for Pathology for Years 4, 5 and 6 of the Cambridge Medical Course, I also lead on the Year 5 written assessments for the Final MB Part II. I have a significant interest in medical education, in particular in the use of learning technology to enhance pathology learning.

I provide clinical sessions in paediatric pathology at CUHNHSFT. My particular fields of interest are solid and haematological paediatric neoplasms.

Research

Paediatric Tumours

Paediatric Lymphoma

Publications

Key publications:

Lymphoreticular Pathology

Anaplastic large cell lymphoma arises in thymocytes and requires transient TCR expression for thymic egress.

Malcolm TI, Villarese P, Fairbairn CJ, Lamant L, Trinquand A, Hook CE, Burke GA, Brugières L, Hughes K, Payet D, Merkel O, Schiefer AI, Ashankyty I, Mian S, Wasik M, Turner M, Kenner L, Asnafi V, Macintyre E, Turner SD.

Nat Commun. 2016 Jan 12;7:10087. doi: 10.1038/ncomms10087.

PMID:

26753883

Cold antibody autoimmune haemolytic anaemia in a child with diffuse large B cell lymphoma.

Uzunova L, Hook CE, Gattens M, Burke GA.

Ann Hematol. 2016 Jan;95(1):151-2. doi: 10.1007/s00277-015-2498-5. No abstract available.

PMID:

26365160

Anaplastic large cell lymphoma-propagating cells are detectable by side population analysis and possess an expression profile reflective of a primitive origin.

Moti N, Malcolm T, Hamoudi R, Mian S, Garland G, Hook CE, Burke GA, Wasik MA, Merkel O, Kenner L, Laurenti E, Dick JE, Turner SD.

Oncogene. 2015 Apr 2;34(14):1843-52. doi: 10.1038/onc.2014.112.