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Department of Pathology

 
Read more at: McGovern Lab wins European Research Council Consolidator Grants

McGovern Lab wins European Research Council Consolidator Grants

2 February 2023

Dr Naomi McGovern of the Department of Pathology and the Centre for Trophoblast Research has been awarded a European Research Council (ERC) Consolidator Grant The grant will support PMDR: Placental macrophages: Their development and role in the placenta. My team’s research focus is human placental macrophage biology. We...


Read more at: New Professor of Pathology appointed

New Professor of Pathology appointed

13 January 2023

The Department of Pathology is delighted to announce the appointment of a new Professor of Pathology, Adrian Liston FMedSci. liston_crop.jpg After an extensive search that attracted many exceptional candidates, we are delighted to have recruited Adrian Liston as our new Professor of Pathology. Professor Liston has an...


Read more at: First approved immunotherapy for melanoma triggers potent anti-tumour responses

First approved immunotherapy for melanoma triggers potent anti-tumour responses

2 December 2022

An IL-2 variant that is more tolerant of the acidic tumour environment improves immunotherapy in mice with melanoma. Researchers have created a variant of human IL-2 that can overcome challenges it experiences in the low-pH environment of tumours, boosting its ability to promote CD8 T cell and natural killer (NK) cell...


Read more at: New MPhil in Biological Sciences

New MPhil in Biological Sciences

11 November 2022

The MPhil in Biological Sciences by Advanced Study is a full-time programme offering students the opportunity to undertake a period of study and lab-based research in an area of scientific importance and interest. Here at Pathology, we will be offering the Infection Biology and Molecular Immunology pathway. The COVID-19...


Read more at: Roychoudhuri group identifies novel negative regulators of natural killer cell-mediated anti-metastatic immunity

Roychoudhuri group identifies novel negative regulators of natural killer cell-mediated anti-metastatic immunity

26 October 2022

Natural killer (NK) cells are critical to immune surveillance against infections and cancer. Their role in immune surveillance requires that NK cells reside within tissues in a quiescent state. The mechanisms by which NK cells remain quiescent in tissues are incompletely understood. The transcriptional repressor BACH2...


Read more at: Advancing clinical and translational research in germ cell tumours
germ cell cancer

Advancing clinical and translational research in germ cell tumours

26 October 2022

The Malignant Germ Cell International Consortium (MaGIC) has just published its recommendations set on advancing the field of germ cell tumours through integrative translational research, led by senior author Professor Matthew Murray from the Department of Pathology. The authors provide insights on how to address the...


Read more at: How can poetry explore and share pathology research with the public?

How can poetry explore and share pathology research with the public?

11 October 2022

Podcast host Rebekah King speaks with David Cain and researchers at the University of Cambridge about their participation in the Creative Encounters Words programme. Listen now to researchers Dr Catherine Merrick (Senior Lecturer Pathology, Biological Sciences), Anne Thomas (Newnham College and Plant Sciences) and Mona...


Read more at: Local immune recognition of trophoblast in early human pregnancy

Local immune recognition of trophoblast in early human pregnancy

4 October 2022

A new review published in Nature by Professor Ashley Moffett and Norman Shreeve focuses on the local interactions that occur early in pregnancy between placental trophoblast cells and maternal uterine immune cells. The cells which are crucial for healthy pregnancy are the subject of many questions and the role of the...


Read more at: New insights into bacterial protein trafficking

New insights into bacterial protein trafficking

7 September 2022

The Koronakis group has published a study that provides new insights into a protein trafficking system essential for the survival and pathogenicity of many bacteria. The work has the potential to aid the development of new antibiotics. Present in all bacteria, lipoproteins are anchored in the membrane by lipid chains and...


Read more at: MRC Multimodal award for integrated human disease research

MRC Multimodal award for integrated human disease research

20 July 2022

The Medical Research Council (MRC) has awarded £7 million towards seven new collaborative research projects aiming to understand human diseases better. The complexities of human physiology mean that many components work within the body, across different scales (from molecules and cells to tissues, organisms and our...