News

A recent study published by the Koronakis Lab has revealed an unexpected finding. We usually think of proteins as little machines that need to be “switched on” to work. But in our recent study, we found something unexpected—some proteins can still affect cell behaviour even when they’re turned off. PAK proteins regulate how cells grow, move, and d…

Celebrating Professor Ming Du’s 2025 Doniach LectureLast week, pathologists across the UK and Ireland gathered for the annual Doniach Lecture, one of the Pathological Society of Great Britain & Ireland’s flagship events. This year, we were honoured to welcome Professor Ming‑Qing Du as the distinguished recipient and speaker.According to the Society…

When people imagine the life of a cutting-edge scientist, they might picture lab coats, late-night research, and groundbreaking discoveries. What they often don’t see is a toddler tugging at a parent’s sleeve or the careful calculus of who picks up the child from daycare. For Professor Adrian Liston, an immunologist at the University of Cambridge, …

We are thrilled to congratulate the following colleagues on their successful promotions under the University’s Academic Career Pathways (ACP) framework:Clinical ProfessorshipDr Catherine Elizabeth Hook, HO Promoted to Clinical Professor in recognition of her excellence in clinical/scientific work and honorary consultant status, aligned with Grad…

The Department of Pathology recently celebrated the successful launch of the Pathogen Cryo-Imaging Facility (PaCIFiC), drawing over 40 attendees from across the University. Researchers from Biochemistry, Genetics, and Pharmacology joined to explore the facility’s state-of-the-art capabilities in cryo-confocal imaging, cryo-CLEM, and GP2 plunge free…

Experts warn of serious health risks of using exosome products that are harvested from human donors.Banned biological products harvested from human cells are being used in UK beauty clinics, according to experts who warn that the luxury treatments could carry serious health risks.Exosomes have been touted as the latest “miracle” skincare treatment,…

A pioneering artificial intelligence (AI) tool developed in Cambridge has demonstrated its potential to revolutionize the diagnosis of coeliac disease, significantly accelerating the process and alleviating pressure on healthcare systems.  The groundbreaking study, published in the New England Journal of Medicine, showcases how AI can automate the …

Professor Ming-Qing Du from the University of Cambridge conducted a pivotal review of the pathogenesis of extranodal marginal zone lymphoma (EMZL). This study, published in Blood, sheds new light on the molecular mechanisms underlying EMZL and provides a framework for future research.EMZL, a type of B-cell lymphoma, arises in mucosa-associated lymp…

In collaboration with Diamond Light Source and other institutions, researchers from the University of Cambridge have employed advanced imaging techniques to elucidate the roles of nine structural proteins in the assembly and nuclear egress of herpes simplex virus-1 (HSV-1).This study integrates cryo-light microscopy and soft X-ray tomography, offer…

Malaria is one of the world’s deadliest infectious diseases, caused by tiny parasites of the Plasmodium genus.While much research focuses on how to kill these parasites, scientists are still uncovering their unique biology. A recent study has revealed surprising details about how Plasmodium parasites replicate their DNA, findings that could have si…

A new study published in Nature has uncovered a novel mechanism by which aspirin inhibits cancer metastasis by strengthening the body’s immune response. Researchers at the University of Cambridge and international collaborators have demonstrated that aspirin enhances T-cell immunity by counteracting platelet-derived thromboxane A2 (TXA2), suppressi…

The WHO describes malaria as 'perpetuating a vicious cycle of inequity'. What are we doing to fight spread and infection?Professor Catherine Merrick comments in the latest episode of the EU's CORDIScovery podcast. Listen here>>

New research from the Department of Pathology, University of Cambridge and CRUK Cambridge Centre Paediatric Cancer Programme members have identified a set of microRNAs in malignant germ cell tumours (GCTs), which may provide new treatment options for patients.  In this work, now published in the Molecular Oncology journal, the team identified a mic…

We are delighted to announce that Professor Ashley Moffett has been awarded Companion of the Order of St Michael and St George in the King's New Year's Honours.Professor Ashley Moffett, Professor of Reproductive Immunology at the University of Cambridge, was awarded the prestigious CMP for services to Women’s Reproductive Health and Clinical Resear…

DNA replication in humans requires precise regulation to ensure accurate genome duplication and maintain genome integrity. A key indicator of this regulation is replication timing, which reflects the interplay between origin firing and fork dynamics.We present a high-resolution (1-kilobase) mathematical model that maps firing rate distributions to …