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Department of Pathology

 
Read more at: Beauty clinics in UK offering banned treatments derived from human cells

Beauty clinics in UK offering banned treatments derived from human cells

31 March 2025

Experts warn of serious health risks of using exosome products that are harvested from human donors. Banned biological products harvested from human cells are being used in UK beauty clinics, according to experts who warn that the luxury treatments could carry serious health risks. Exosomes have been touted as the latest “...


Read more at: AI Technology Offers Breakthrough in Coeliac Disease Diagnosis

AI Technology Offers Breakthrough in Coeliac Disease Diagnosis

25 March 2025

A pioneering artificial intelligence (AI) tool developed in Cambridge has demonstrated its potential to revolutionize the diagnosis of coeliac disease, significantly accelerating the process and alleviating pressure on healthcare systems. The groundbreaking study, published in the New England Journal of Medicine, showcases...


Read more at: Groundbreaking Review Unveils New Molecular Insights into Extranodal Marginal Zone Lymphoma

Groundbreaking Review Unveils New Molecular Insights into Extranodal Marginal Zone Lymphoma

10 March 2025

Professor Ming-Qing Du from the University of Cambridge conducted a pivotal review of the pathogenesis of extranodal marginal zone lymphoma (EMZL). This study, published in Blood , sheds new light on the molecular mechanisms underlying EMZL and provides a framework for future research. EMZL, a type of B-cell lymphoma...


Read more at: Innovative Imaging Techniques Unveil New Insights into Herpes Simplex Virus-1 Assembly

Innovative Imaging Techniques Unveil New Insights into Herpes Simplex Virus-1 Assembly

5 March 2025

In collaboration with Diamond Light Source and other institutions, researchers from the University of Cambridge have employed advanced imaging techniques to elucidate the roles of nine structural proteins in the assembly and nuclear egress of herpes simplex virus-1 (HSV-1). This study integrates cryo-light microscopy and...


Read more at: How DNA replication in malaria parasites could shape new treatments

How DNA replication in malaria parasites could shape new treatments

5 March 2025

Malaria is one of the world’s deadliest infectious diseases, caused by tiny parasites of the Plasmodium genus. While much research focuses on how to kill these parasites, scientists are still uncovering their unique biology. A recent study has revealed surprising details about how Plasmodium parasites replicate their DNA...


Read more at: Groundbreaking study reveals Aspirin’s potential to prevent cancer metastasis by boosting immune response

Groundbreaking study reveals Aspirin’s potential to prevent cancer metastasis by boosting immune response

5 March 2025

A new study published in Nature has uncovered a novel mechanism by which aspirin inhibits cancer metastasis by strengthening the body’s immune response. Researchers at the University of Cambridge and international collaborators have demonstrated that aspirin enhances T-cell immunity by counteracting platelet-derived...


Read more at: Saving lives by tackling Malaria

Saving lives by tackling Malaria

20 February 2025

The WHO describes malaria as 'perpetuating a vicious cycle of inequity'. What are we doing to fight spread and infection? Professor Catherine Merrick comments in the latest episode of the EU's CORDIScovery podcast. Listen here>>


Read more at: Developing kinder treatments for patients with germ cell tumours

Developing kinder treatments for patients with germ cell tumours

8 January 2025

New research from the Department of Pathology, University of Cambridge and CRUK Cambridge Centre Paediatric Cancer Programme members have identified a set of microRNAs in malignant germ cell tumours (GCTs), which may provide new treatment options for patients. In this work, now published in the Molecular Oncology journal...


Read more at: Professor Ashley Moffett awarded Companion of the Order of St Michael and St George

Professor Ashley Moffett awarded Companion of the Order of St Michael and St George

7 January 2025

We are delighted to announce that Professor Ashley Moffett has been awarded Companion of the Order of St Michael and St George in the King's New Year's Honours. Professor Ashley Moffett , Professor of Reproductive Immunology at the University of Cambridge, was awarded the prestigious CMP for services to Women’s...


Read more at: DNA replication timing reveals genome-wide features of transcription and fragility

DNA replication timing reveals genome-wide features of transcription and fragility

16 December 2024

DNA replication in humans requires precise regulation to ensure accurate genome duplication and maintain genome integrity. A key indicator of this regulation is replication timing, which reflects the interplay between origin firing and fork dynamics. We present a high-resolution (1-kilobase) mathematical model that maps...