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Department of Pathology

 
Read more at: Herpes Simplex Virus-1 Transactivator Infected Cell Protein-4 Drives VEGF-A Dependent Neovascularization
Herpes Simplex Virus-1 Transactivator Infected Cell Protein-4 Drives VEGF-A Dependent Neovascularization

Herpes Simplex Virus-1 Transactivator Infected Cell Protein-4 Drives VEGF-A Dependent Neovascularization

12 December 2013

6 October 2011 The Herpes Simplex Virus-1 Transactivator Infected Cell Protein-4 Drives VEGF-A Dependent Neovascularization. Dr Stacey Efstathiou has collaborative paper published in PLoS Pathogens. Transmission Electron Microscopy image of Herpes simplex virus type 1 Courtesy of Dr Colin Crump. Read more


Read more at: Out of Africa: what is an allergen?
Out of Africa: what is an allergen?

Out of Africa: what is an allergen?

12 December 2013

9 January 2011 Some fundamental questions in allergy remain unanswered. Among them are ‘What exactly is an allergen?’ and ‘Why is the immune response so similar to that against parasitic worms?’ Trust-funded researchers are examining the problems through an evolutionary lens. By Penny Bailey Film lovers will be familiar...


Read more at: New mechanism to control the actin cytoskeleton of the mammalian cell

New mechanism to control the actin cytoskeleton of the mammalian cell

12 December 2013

8 August 2011 Animal and plant cells contain a dynamic network of actin filaments, which are assembled and disassembled to drive fundamental processes such as cell migration, phagocytosis, synapse plasticity and tissue repair, and also pathologies like tumour and pathogen invasion. Prof Vassilis Koronakis and colleagues...


Read more at: Common gene fault triggers more aggressive cervical cancer
Common gene fault triggers more aggressive cervical cancer

Common gene fault triggers more aggressive cervical cancer

12 December 2013

19 May 2011 Common gene fault triggers a ripple of molecular signals leading to more aggressive cervical cancer . Cancer Research UK scientists have discovered that a common gene fault in cervical cancer cells triggers a ripple of molecular signals - which makes the disease more aggressive, according to research published...


Read more at: 10,000th structure curated by the Protein Data Bank in Europe

10,000th structure curated by the Protein Data Bank in Europe

12 December 2013

4 February 2011 The Protein Data Bank in Europe (PDBe) has annotated its 10 000th structure for inclusion in the Protein Data Bank (PDB), a freely available resource for life science researchers. Gerard Kleywegt, Head of PDBe, tells us about the project and what's special about this milestone structure. PDBe is part of the...


Read more at: Researchers Publish Breakthrough in Understanding Cancer Cell Death

Researchers Publish Breakthrough in Understanding Cancer Cell Death

12 December 2013

22 February 2011 Pathology researchers publish in Nature Cell Biology exciting breakthrough for the understanding of cell death and the treatment of cancers that are resistant to cell death . The work was carried out primarily by two PhD students in Christine Watson’s lab; the first author Peter Kreuzaler was funded by a...


Read more at: Department researchers Reveal How Membrane Efflux Pumps Open To Confer Multidrug Resistance and Virulence on Bacteria

Department researchers Reveal How Membrane Efflux Pumps Open To Confer Multidrug Resistance and Virulence on Bacteria

12 December 2013

21 January 2011 Department researchers reveal in PNAS how membrane efflux pumps open to confer multidrug resistance and virulence on bacteria. Published this month: Pei X-Y, Hinchliffe P, Symmons M, Koronakis E, Hughes C, Koronakis V (2011) Structures of sequential open states in a symmetrical opening transition of the...


Read more at: Prof Anne Cooke awarded honorary doctorate by University of Copenhagen, Faculty of Life Sciences.

Prof Anne Cooke awarded honorary doctorate by University of Copenhagen, Faculty of Life Sciences.

12 December 2013

The University of Copenhagen was founded in 1479 and ever since, it has celebrated its foundation with an annual commemoration. The Commemoration, at which Prof Cooke was awarded her honorary doctorate from the University of Copenhagen, took place on 18 November 2010 at the University's Ceremonial Hall in Copenhagen in the...


Read more at: Cambridge iGEM 2010 Success
Cambridge iGEM 2010 Success

Cambridge iGEM 2010 Success

12 December 2013

Out of over 120 teams the Cambridge iGEM team made the final six. They won the best Wiki prize, iGEMers prize (most helpful team) and a gold medal for the high standard of project results, reporting, contribution of resources. As a future projection, the team made a computational model that estimated that 0.02% of daylight...


Read more at: Cambridge scientists help African science to THRiVE
Cambridge scientists help African science to THRiVE

Cambridge scientists help African science to THRiVE

12 December 2013

More than 80 Cambridge researchers have signed up to take their research expertise to Africa to strengthen health research on the continent. Read more