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Department of Pathology

 
Read more at: What makes T cells sticky?

What makes T cells sticky?

20 July 2022

A new publication sets out to figure out what makes T cells stick Many genetic and biochemical pathways are highly conserved in all living organisms. One such pathway is the so-called PI3K pathway, an ancient nutrient-sensing pathway found in worms, flies and humans. Its simplest manifestation involves three protein...


Read more at: Prestigious European Research Council (ERC) Consolidator Grant awarded

Prestigious European Research Council (ERC) Consolidator Grant awarded

15 June 2022

Dr Rahul Roychoudhuri and his team have been awarded the prestigious European Research Council (ERC) Consolidator Grant award Rahul and his team were awarded €1.8 million for their research aiming to break new ground in understanding how inflammatory responses are kept in check by regulatory T (Treg) cells...


Read more at: Outstanding academic contributions and achievements recognised

Outstanding academic contributions and achievements recognised

15 June 2022

We are delighted to announce that five researchers in Pathology have successfully completed the Academic Career Pathways scheme and been selected for promotion. The University of Cambridge is committed to providing a supportive environment to enable individuals to take ownership of their development and build successful...


Read more at: Results of the Research Excellence Framework (REF)

Results of the Research Excellence Framework (REF)

31 May 2022

Results show our research is as strong, inclusive and impactful as ever. This is the University’s most inclusive REF submission to date. Eligible researchers across all academic disciplines were assigned to one of 30 units of assessment (subject areas). The overall quality profile awarded is a weighted combination of three...


Read more at: Exploring the utility of X-ray tomography for virus research

Exploring the utility of X-ray tomography for virus research

12 April 2022

Most ultrastructural herpesvirus research is done using transmission electron microscopy—however, research led by Kamal Nahas and collaborators from Stephen Graham's Laboratory and Colin Crump's Laboratory has demonstrated that an emerging imaging technique, known as cryo-soft-X-ray tomography, could also be used and has a...


Read more at: Cambridge Festival: Germ Hide and Seek

Cambridge Festival: Germ Hide and Seek

6 April 2022

When germs such as viruses get into our bodies they often hide inside our cells. Our immune system is there to help you seek out pesky pathogens. In this challenge, your job is to be your immune system. Find the cells with germs hiding in the cells. Our researchers in the Boyle Lab have developed this fun game as part of...


Read more at: Event: DNA Tumour Virus 2022

Event: DNA Tumour Virus 2022

4 April 2022

Join us in Cambridge for DNA Tumour Virus 2022! The DNA Tumour Virus Meeting (DNA TVM) brings together a diverse group of researchers with shared research interests in the study of DNA tumour viruses. These viruses include the polyomaviruses, papillomaviruses, and adenoviruses which have proved to be invaluable models in...


Read more at: A new tool to clean, interpret and visualise aligned sequences

A new tool to clean, interpret and visualise aligned sequences

16 March 2022

Researchers at Pathology have devised a highly customisable command-line tool to clean, interpret and visualise multiple sequence alignments CIAlign effectively removes problematic regions and sequences from MSAs and provides novel visualisation options. This tool can be used to fine-tune alignments for further analysis...


Read more at: Researcher Spotlight: Nerea Irigoyen

Researcher Spotlight: Nerea Irigoyen

15 March 2022

Pathology researcher, Nerea Irigoyen, shares her experience contributing to the global pandemic research effort. In March 2020, at the start of the pandemic, Nerea had to postpone all her Zika research work. She took this opportunity to apply her work in reversing cell stress response to reduce virus replication to SARS-...


Read more at: How vaccinia virus tricks the immune system to escape antiviral defences

How vaccinia virus tricks the immune system to escape antiviral defences

7 January 2022

Jonas Dutra Albarnaz and Geoffrey L Smith Researchers from the Department of Pathology and the Gurdon Institute have uncovered a new mechanism by which pathogenic viruses antagonise our immune defences. Using molecular mimicry, the protein F14 from vaccinia virus (VACV) disables the immune response to inflammatory signals...