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suzanne turner

stacey efstathiou


Salmonella (small red cells) establishes its SCV niche (green) in a human cell (stained by cytoskeleton in blue, nucleus in red).


New Aid In Diabetes Study

Figure 1: (a) Incidence of diabetes in female NOD mice from the colony in the Pathology Department, Cambridge (NOD CAM) and female NOD ES cell progeny of the chimeras deriving from all three ES cell lines tested.

Pancreas sections

Figure 1: (b) Immunohistochemical analysis of pancreas sections from 12-week-old female mice stained for CD3 (green) and insulin (red). Top left, section of pancreas from a female NOD CAM mouse. Top right, bottom left and bottom right, sections of pancreas from progeny of chimeras generated using ES cell lines 1, 2 and 3, respectively. Scale bars, 50 µm

Cambridge Team

iGEM competition

iGEM competition

Science Day in Pathology

Science Day in Pathology

Department's Teaching Lab

Department's Teaching Lab

High Resolution Digital Image

High Resolution Digital Image

Professor Ann Cook

Professor Ann Cook


Crystal structures

Figure: Crystal structures of the TolC entrance closed state wildtype WT and transitions to the initial and advanced open states RS and YFRS




2yf6. MHC is in green, b2 microglobulin in blue, peptide bound to MHC in spacefill, coloured by atom

Phospholipid membrane-coated beads

Figure: Phospholipid membrane-coated beads, incubated in a brain cell extract, assemble actin "comet tails" (red) which propel the beads through the extract.

Portal vein of an experimental mouse host

A macroscopic view of the portal vein of an experimental mouse host. The blood vessel contains a coiled Schistosoma mansoni worm pair. Credit: Wellcome Library, London.

Two grains of pollen from a peony

Two grains of pollen from a peony. Credit: Annie Cavanagh, Wellcome Images.

Human pre-implantation embryos developing in vitro.

Human pre-implantation embryos developing in vitro. Following fertilization, the embryo divides while remaining within the translucent zona pellucida (zp, arrowed). Shown are the 8 cell stage (d), the early morula stage of approximately 16 cells (e), the early blastocyst stage (f) - note the fluid filled blastocoelic cavity and the small cluster of cells at the top which will develop into the fetus. (g) shows the blastocyst hatching through the zona at the top left, and (h) shows the hatched blastocyst with the empty zona lying beneath it. The hatched blastocyst is now ready to attach to the luminal epithelium, which lines the uterus. It is this attachment process that is disrupted when SGK1 expression in the epithelium is abnormally high. (photographs courtesy of Professor Peter Braude and Professor Martin Johnson, published in Essential Reproduction).

Drosophila Cell

Figure: Drosophila cell in cytokinesis stained to detect DNA (blue), microtubules (red), and myosin (green) to mark the contractile ring.


Fig: Salmonella (blue) triggering Arf-enriched membrane ruffles (red)

Dr Matthew Murray

Dr Matthew Murray

Cross section of a Mammary Duct

Fig: A cross-section of a mammary duct showing the outer layer of basal cells (stained with an antibody to Keratin 14 (green) and the inner layer of luminal cells (stained with an antibody to Keratin 18 (red). Nuclei are in blue. The Zfp157 gene is expressed in the basal layer and controls lineage commitment of the luminal cells.

Quote by Prof Sir Leszek Borysiewicz

- Prof. Sir Leszek Borysiewicz


Murray Cambridge bench

Dr Matthew Murray


Super res imaging hsv-a

Super res imaging hsv-a-250

2015 Dept Symposium Poster Winners





Modern Pathology

Doorbar Modern Pathology

Blood Smear (Laman)

Ebola lab





Nature cover 15-11-18




Dysregulated microRNA (miRNA) expression in malignant germ cell tumours. miRNAs from the miR-371∼373 and miR-302/367 clusters (red boxes) are over-expressed in malignant GCTs. Downregulated microRNAs include those from the let-7 family as well as miR-99a, miR-100, and miR-125b (blue boxes). Mechanisms that potentially underly these changes are shown in grey boxes. miRNA dysregulation may be exploited clinically through serum miRNA testing for over-expressed miRNAs (green oval) or therapeutic targeting of overexpressed miRNAs and/or replenishment of under-expressed miRNAs (orange ovals).




Advice for staff and students at the University and Colleges on novel coronavirus (COVID-19). The University is continually monitoring latest Public Health England and government advice about the virus.

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Safe Space Information

In collaboration with the University Safe Space team, the department has generated a Return to the Workplace document that outlines the current social distancing measures which are in place to protect the safety and welfare of you and others. This document is updated frequently as guidance changes.