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Department of Pathology

 

Research

Zika virus titrationsUnderstanding the role of Zika virus genome translation in viral pathogenicity and disease:
• Understanding how virus translation is regulated.
• Understanding the impact of changes in virus genome translation on virus virulence, disease and viral tropism.

Group members:

Eliza Walker (Harry Smith summer student)
César Palacios (Erasmus+ summer student)
Gema Martínez (Erasmus+ summer student)
Charlotte Lefèvre (Wolfson-Pathology PhD student)

Publications

Key publications: 

1. Irigoyen, N., Dinan, AM., Meredith, LW., Goodfellow, I., Brierley, I., Firth, AE. The translational landscape of Zika virus during infection of mammalian and insect cells. (preprint; bioRxiv: doi:10.1101/112904).

2. Irigoyen, N., Dinan, AM., Brierley, I., Firth, AE. Ribosome profiling of the retrovirus murine leukemia virus. Retrovirology. 2018 Jan 22; 15(1):10.

3. Irigoyen, N., Firth, AE., Jones, JD., Chung, BY., Siddell, SG., Brierley, I. High-resolution analysis of coronavirus gene expression by RNA sequencing and ribosome profiling. PLoS Pathog. 2016 Feb 26; 12(2):e1005473

Research Group Leader
Division of Virology
Dr Nerea  Irigoyen

Contact Details

Division of Virology
Lab Block Level 5 (BOX 237)
Department of Pathology, University of Cambridge
Addenbrooke's Hospital, Hills Road
Cambridge, CB2 0QQ
United Kingdom
+44 (0) 1223 3 36914
Not available for consultancy

Affiliations