Professor Colin Crump

Our laboratory studies virus-cell interactions with a focus on the assembly and egress of viruses ane the wide variety of cellular pathways modified by viruses to establish infection and spread to new cells. We currently study three families of viral pathogens: herpesviruses, polyomaviruses and bunyaviruses. In particular, we seek to understand how herpes simplex virus, BK polyomavirus and Oropouche virus interact with and modify host cells to reprogram them into efficient factories for producing and disseminating new virions.

Our laboratory collaborates widely and employs a range of techniques to gain a multi-faceted understanding of virus replication, including advanced microscopy imaging, proteomics, and genome-wide genetic screens.