Dr Luay Joudeh

Dr Luay Joudeh is an interdisciplinary scientist with deep expertise in biochemistry, biophysics, and advanced microscopy. His research spans the molecular mechanisms of DNA replication and repair, as well as the development and application of cutting-edge imaging technologies to interrogate biological processes at high resolution.

With a strong foundation in single-molecule imaging, Luay has developed and applied a wide range of techniques, including Förster Resonance Energy Transfer (FRET), single-particle tracking, super-resolution microscopy, and optical tweezers–based confocal microscopy. He has also pioneered applications of label-free force spectroscopy to study molecular interactions and conformational dynamics in real time.

In recent years, Luay has expanded his expertise into cryo-electron microscopy (cryo-EM), particularly single-particle analysis, and is currently leading the establishment of cryo-confocal correlative imaging workflows in Cambridge. His goal is to integrate these approaches with cryo-electron tomography (cryo-ET) and 3D cellular imaging to enable high-resolution structural and contextual insights into pathogen–host interactions and intracellular architecture.

He is a strong advocate for methodological innovation and cross-disciplinary collaboration, and currently manages the Pathogen Cryo-Imaging Facility (PaCIFiC) at the University of Cambridge, helping researchers across the biological sciences access advanced cryogenic imaging platforms.

For a full list of publications and further information, please visit his ORCID profile.

Areas of Interest