Department of Pathology

The Department of Pathology is one of the largest Departments in the School of Biological Sciences, and a leading research institution with a yearly research income of £9M. The Department's research seeks to understand - and so ultimately arrest and reverse - disease processes of medical and social significance. The work of the Department is organised into five Divisions: Cell and Molecular Pathology, Immunology, Microbiology and Parasitology, Virology and Molecular Histopathology, split between the University site and Addenbrooke's Hospital, as well as undertaking cross-disciplinary research with colleagues at Research Institutes including the Cambridge Institute for Medical Research and the Hutchison-MRC Institute for Cancer Research.

The Department also has a major yearly commitment in the teaching and training to over 800 undergraduate students of medicine and of veterinary and natural science. In its research laboratories it provides training for over 70 graduate students. Members of the Department also contribute, together with colleagues in the National Health Service and Health Protection Agency, to provision of diagnostic services within Addenbrooke's Hospital and the Anglia Region.

Latest talks ...
Thu 18 Sep
The role of macrophages in tumour progression and metastasis
Jeffrey Pollard, University of Edinburgh and Albert Einstein College of Medicine, New York
Tue 30 Sep
Cambridge Immunology Forum 2014
Erika Pearce, Ajay Chawla, Karine Clément, Luke O’Neill, Doreen Cantrell, Mala Maini, Ziad Mallat, Toni Vidal-Puig
Fri 10 Oct
Neutrophil transmigration in vivo: Mechanisms, dynamics and pathogenesis
Sussan Nourshargh, William Harvey Research Institute Barts & The London School of Medicine and Dentistry Queen Mary, University of London
Fri 24 Oct
The human leukaemia virus HTLV-1: clonality, latency and immune response.
Prof. Charles Bangham ( Imperial College London)
Announcements
News and Events

Many congratulations to Drs Gillian Fraser and Suzanne Turner on their promotion to Senior Lecturer.

Gillian works on the molecular cell biology of pathogenic bacteria. She has a longstanding interest in bacterial motility and, together with colleagues in the Department's molecular, structural and cellular microbiology unit, she recently uncovered a completely new and unanticipated mechanism that explains how bacteria build complex flagella 'nanomotors' far outside the bacterial cell which was published in Nature and featured on this site. Gillian is also a Fellow and Director of Studies for the Biological Natural Sciences at Queens' College.

Suzanne’s lab carries out research into childhood cancer, in particular lymphoma a cancer of the immune system and is supported with funding from Leukaemia and Lymphoma Research and the Alex Hulme Foundation. Most recently, Suzanne’s lab has shown that a type of childhood lymphoma called Anaplastic large Cell Lymphoma is structured much like a bee hive with the ‘Queen bees’, or cancer stem cells not only giving rise to the bulk tumour population but also supporting its growth. These Queen bee tumour cells account for less than 3% of the total tumour mass and it is these that should be the target of future treatments. Indeed, in this work recently published in the journal Oncogene, Suzanne’s team have shown that a relatively new drug called Crizotinib is effective at killing the cancer stem cells; the next step is to implement a clinical trial within Europe.