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Doorbar Research

Our past work has identified important changes in viral gene expression that underlie the development of HPV-associated cervical intraepithelial neoplasias (top left). A series of molecular studies that we have published in the Journal of Virology over the last few years has revealed how one of the viral proteins (E4) is post-transcriptionally modified to facilitate its deposition as amyloid-like fibrils (bottom left). An image of E4 staining in a patient biopsy of a cervical neoplasia prepared using a cross-reactive E4 antibody prepared in the lab is shown in the MRC Strategic Plan to illustrate to potential of such research in the development of diagnostic strategies for disease stratification.
Doorbar Research
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Advice for staff and students at the University and Colleges on novel coronavirus (COVID-19). The University is continually monitoring latest Public Health England and government advice about the virus.

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Safe Space Information

In collaboration with the University Safe Space team, the department has generated a Return to the Workplace document that outlines the current social distancing measures which are in place to protect the safety and welfare of you and others. This document is updated frequently as guidance changes.