Research Associate
Queens' College PDRA
Structural Microbiologist
Tennis Court Road
Cambridge
Cambridgeshire
CB2 1QP
Websites:
Key Publications
EFFLUX PUMPS
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Structure and Mechanotransmission mechanism of the MacB ABC Transporter Superfamily
A Crow, NP Greene, E Kaplan, V Koronakis Proceedings of the National Academy of Sciences (2017)
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Structure of an atypical periplasmic adaptor from a multidrug efflux pump of the spirochete Borrelia burgdorferi
NP Greene, P Hinchliffe, A Crow, A Ababou, C Hughes, V Koronakis FEBS letters 587 (18), 2984-2988 (2013) -
Structure of the periplasmic adaptor protein from a major facilitator superfamily (MFS) multidrug efflux pump
P Hinchliffe, NP Greene, NG Paterson, A Crow, C Hughes, V Koronakis FEBS letters 588 (17), 3147-3153 (2014)
NITRIC OXIDE REDUCTASE
- Structure of the membrane-intrinsic nitric oxide reductase from Roseobacter denitrificansAllister Crow, Yuji Matsuda, Hiroyuki Arata, and Arthur Oubrie Biochemistry (2016)
BACTERIAL TOXIN ACTIVATION
- Structure of a bacterial toxin-activating acyltransferase
NP Greene*, A Crow*, C Hughes, V Koronakis Proceedings of the National Academy of Sciences (2015)
BACTERIAL EFFECTOR PROTEINS
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The molecular basis of ubiquitin-like protein NEDD8 deamidation by the bacterial effector protein Cif
A Crow, RK Hughes, F Taieb, E Oswald, MJ Banfield Proceedings of the National Academy of Sciences 109 (27), E1830-E1838 (2012) -
Crystal structures of Cif from bacterial pathogens Photorhabdus luminescens and Burkholderia pseudomallei
A Crow, PR Race, G Jubelin, CV Chavez, JM Escoubas, E Oswald, MJ Banfield PLOS one 4 (5), e5582 (2009)
CYTOCHROME C MATURATION
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Effects of substitutions in the CXXC active-site motif of the extracytoplasmic thioredoxin ResA
A Lewin, A Crow, C Hodson, L Hederstedt, N Le Brun Biochem. J 414, 81-91 (2008) - Molecular basis for specificity of the extracytoplasmic thioredoxin ResA
A Lewin, A Crow, A Oubrie, NE Le Brun Journal of Biological Chemistry 281 (46), 35467-35477 (2006)
- The role of ResA in type II cytochrome c maturation
A Crow, NE Le Brun, A Oubrie Biochemical Society Transactions 33 (1), 149-151 (2005)
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Structural basis of redox-coupled protein substrate selection by the cytochrome c biosynthesis protein ResA
A Crow, RM Acheson, NE Le Brun, A Oubrie Journal of Biological Chemistry 279 (22), 23654-23660 (2004)
BACTERIOFERRITIN
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Iron core mineralisation in prokaryotic ferritins
NE Le Brun, A Crow, MEP Murphy, AG Mauk, GR Moore Biochimica et Biophysica Acta 1800 (8), 732-744 (2010) -
Structural basis for iron mineralization by bacterioferritin
A Crow, TL Lawson, A Lewin, GR Moore, NE Le Brun Journal of the American Chemical Society 131 (19), 6808-6813 (2009) -
Monitoring the iron status of the ferroxidase center of Escherichia coli bacterioferritin using fluorescence spectroscopy
TL Lawson, A Crow, A Lewin, S Yasmin, GR Moore, NE Le Brun Biochemistry 48 (38), 9031-9039 (2009)
THIOL:DISULFIDE OXIDOREDUCTASES
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Crystal structure and biophysical properties of Bacillus subtilis BdbD An oxidizing thiol: disulfide oxidoreductase containing a novel metal site
A Crow, A Lewin, O Hecht, MC Möller, GR Moore, L Hederstedt, NE Le Brun Journal of Biological Chemistry 284 (35), 23719-23733 (2009) -
Structure and functional properties of Bacillus subtilis endospore biogenesis factor StoA
A Crow, Y Liu, MC Möller, NE Le Brun, L Hederstedt Journal of Biological Chemistry 284 (15), 10056-10066 (2009) -
Structural studies of the ResA and BdbD proteins of Bacillus subtilis
A Crow Thesis - University of East Anglia (2006)
BACTERIAL PILUS FORMATION
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Intramolecular isopeptide but not internal thioester bonds confer proteolytic and significant thermal stability to the S. pyogenes pilus adhesin Spy0125
M Walden, A Crow, MD Nelson, MJ Banfield Proteins: Structure, Function, and Bioinformatics 82 (3), 517-527 (2014) -
A highly unusual thioester bond in a pilus adhesin is required for efficient host cell interaction
JA Pointon, WD Smith, G Saalbach, A Crow, MA Kehoe, MJ Banfield Journal of Biological Chemistry 285 (44), 33858-33866 (2010) -
Crystal structure of Streptococcus pyogenes Sortase A implications for sortase mechanism
PR Race, ML Bentley, JA Melvin, A Crow, RK Hughes, WD Smith, RB Sessions, MA Kehoe, DG McCafferty, MJ Banfield Journal of Biological Chemistry 284 (11), 6924-6933 (2009)