Chromosome 8 breaks in common cancers

Chromosome 8 Derivatives and Their Breakpoints
in Cell Lines from Common Cancers

Rearrangements of chromosome 8 by cell line type:

Breast cancer cell lines
Colorectal cancer cell lines
Pancreatic cancer cell lines
Other cancer cell lines (MDA-MB-435, MT-1, SW979)

work by Amber Alsop and Joanne Staines, as described in

Jessica CM Pole, Celine Courtay-Cahen*, Maria J Garcia, Katherine A Blood, Susanna L Cooke, Amber E Alsop^†, Donald ML Tse, Carlos Caldas and Paul AW Edwards

"High resolution analysis of 8p in breast, colon and pancreatic cancer reveals a complex pattern of loss, gain and rearrangement " Oncogene, in press early 2006

Cancer Genomics Program, Hutchison-MRC Research Centre,
Departments of Pathology and Oncology, University of Cambridge, Cambridge, U.K.

* Current address: Animal Health Trust,
Lanwades Park, Kentford, Newmarket, Suffolk, CB8 7UU

^†Current address: Comparative Genomics Group, Research School of Biological Sciences,
The Australian National University, Canberra ACT 2601 Australia

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updated February 2006