Chromosome 18 breaks in common cancers

Chromosome 18 Derivatives and Their Breakpoints
in Cell Lines from Common Cancers

Overview of rearrangements
(band and arm paints)

Detailed BAC mapping of rearrangements by cell line type:

Breast cancer cell lines
Colorectal cancer cell lines
Pancreatic cancer cell lines
Other cancer cell lines (MDA-MB-435, SW979)

work by Amber Alsop, as described in

Amber E Alsop^†, Andrew Teschendorff and Paul AW Edwards
"Distribution of Breakpoints on Chromosome 18 in Breast, Colorectal and Pancreatic Carcinoma Cell Lines" Cancer Genetics & Cytogenetics, 2006; 164:97-109

Cancer Genomics Program, Hutchison-MRC Research Centre,
Departments of Pathology and Oncology, University of Cambridge, Cambridge, U.K.

^†Current address: Comparative Genomics Group, Research School of Biological Sciences,
The Australian National University, Canberra ACT 2601 Australia

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updated Oct 2005