Breast Cancer Cell Lines: Rearrangements of Chromosome 18



Ideograms summarising FISH results, for each cell line, of a selection of BACs
mapping to chromosome 18.

  • All copies of chromosome 18 are shown, including apparently normal ones.
  • Not all BACS were used for every cell line, so only those used, and which gave a signal, are shown.
  • The identity of the translocation partner is indicated for each derivative.
  • '?' indicates that the translocation partner is unknown.
  • The G-band pattern for chromosome 18 is based on UCSC Genome Browser positions.
  • The position of the BACs is to scale.
  • Filled red triangles indicate approximate positions of breakpoints.
  • Unfilled triangles indicate breakpoints that were not counted in our breakpoint survey (see Alsop et al, 2005) as they either appeared balanced, or the (derivative) chromosome had been duplicated.



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