Other SKY data websites:
SKYWeb collection of SKY karyotype data maintained by NCBI
SKY data on the NCI-60 panel of cell lines
Other M-FISH, array-CGH and cell line data websites:
http://www.med.uni-jena.de/fish/mFISH/mFISHlit.htm
Laurence Berkeley Lab Breast cancer cell line data website
Sanger Institute Cancer Genome Project, SNP6 array-CGH data and Cell line cross-contamination data
References to other SKY and M-FISH data on Cancer Cell Lines and Primary Cancer Samples.
Examples of Papers describing SKY and M-FISH karyotypes of common epithelial cancer cell lines. Those in red report data included, or to be included in the future, on this site.
Grigorova M, Staines JM, Ozdag H, Caldas C, Edwards PA. Possible causes of chromosome instability: comparison of chromosomal abnormalities in cancer cell lines with mutations in BRCA1, BRCA2, CHK2 and BUB1. Cytogenet Genome Res. 2004;104(1-4):333-40. PMID: 15162061
Roschke AV, Tonon G, Gehlhaus KS, McTyre N, Bussey KJ, Lababidi S, Scudiero DA, Weinstein JN, Kirsch IR. Karyotypic complexity of the NCI-60 drug-screening panel. Cancer Res. 2003 Dec 15;63(24):8634-47 (see links above)
Adeyinka A, Kytola S, Mertens F, Pandis N, Larsson C. Spectral karyotyping and chromosome banding studies of primary breast carcinomas and their lymph node metastases. Int J Mol Med. 2000 Mar;5(3):235-40. PMID: 10677562
Davidson JM, Gorringe KL, Chin SF, Orsetti B, Besret C, Courtay-Cahen C, Roberts I, Theillet C, Caldas C, Edwards PA.Molecular cytogenetic analysis of breast cancer cell lines. Br J Cancer. 2000 Nov;83(10):1309-17. PMID: 11044355
Ferti AD, Stamouli MJ, Panani AD, Raptis SA, Young BD. Molecular cytogenetic analysis of breast cancer: a combined multicolor fluorescence in situ hybridization and G-banding study of uncultured tumor cells. Cancer Genet Cytogenet. 2004;149:28-37. PMID: 15104280
Kytola S, Rummukainen J, Nordgren A, Karhu R, Farnebo F, Isola J, Larsson C. Chromosomal alterations in 15 breast cancer cell lines by comparative genomic hybridization and spectral karyotyping. Genes Chromosomes Cancer. 2000 Jul;28(3):308-17.
Popovici, C, Basset, C, Bertucci, F, Orsetti, B, Adelaide, J, Mozziconacci, MJ, Conte, N, Murati, A, Ginestier, C, Charafe-Jauffret, E, Ethier, SP, Lafage-Pochitaloff, M, Theillet, C, Birnbaum, D, Chaffanet, M. Reciprocal translocations in breast tumor cell lines: cloning of a t(3;20) that targets the FHIT gene. Genes Chromosomes Cancer 2002;35(3):204-18
Watson MB, Bahia H, Ashman JN, Berrieman HK, Drew P, Lind MJ, Greenman J, Cawkwell L. Chromosomal alterations in breast cancer revealed by multicolour fluorescence in situ hybridization. Int J Oncol. 2004 Aug;25(2):277-83.
Fadl-Elmula I, Kytola S, Pan Y, Lui WO, Derienzo G, Forsberg L, Mandahl N, Gorunova L, Bergerheim US, Heim S, Larsson C. Characterization of chromosomal abnormalities in uroepithelial carcinomas by G-banding, spectral karyotyping and FISH analysis. Int J Cancer. 2001 Jun 15;92(6):824-31
Padilla-Nash HM, Nash WG, Padilla GM, Roberson KM, Robertson CN, Macville M, Schrock E, Ried T. Molecular cytogenetic analysis of the bladder carcinoma cell line BK-10 by spectral karyotyping. Genes Chromosomes Cancer. 1999 May;25(1):53-9
Harding MA, Arden KC, Gildea JW, Gildea JJ, Perlman EJ, Viars C, Theodorescu D. Functional genomic comparison of lineage-related human bladder cancer cell lines with differing tumorigenic and metastatic potentials by spectral karyotyping, comparative genomic hybridization, and a novel method of positional expression profiling. Cancer Res. 2002 Dec 1;62(23):6981-9
Stamouli MI, Panani AD, Ferti AD, Petraki C, Oliver RT, Raptis SA, Young BD.
Detection of genetic alterations in primary bladder carcinoma with dual-color and multiplex fluorescence in situ hybridization. Cancer Genet Cytogenet. 2004 Mar;149(2):107-13. PMID: 15036885
Strefford JC, Lillington DM, Steggall M, Lane TM, Nouri AM, Young BD, Oliver RT. Novel chromosome findings in bladder cancer cell lines detected with multiplex fluorescence in situ hybridization. Cancer Genet Cytogenet. 2002 Jun;135(2):139-46. PMID: 12127398
Macville M, Schrock E, Padilla-Nash H, Keck C, Ghadimi BM, Zimonjic D, Popescu N, Ried T. Comprehensive and definitive molecular cytogenetic characterization of HeLa cells by spectral karyotyping. Cancer Res. 1999 Jan 1;59(1):141-50. PMID: 9892199
Abdel-Rahman WM, Katsura K, Rens W, Gorman PA, Sheer D, Bicknell D, Bodmer WF, Arends MJ, Wyllie AH, Edwards PA Spectral karyotyping suggests additional subsets of colorectal cancers characterized by pattern of chromosome rearrangement. Proc Natl Acad Sci U S A. 2001 98(5):2538-43. PMID: 11226274
Ghadimi BM, Sackett DL, Difilippantonio MJ, Schrock E, Neumann T, Jauho A, Auer G, Ried T. Centrosome amplification and instability occurs exclusively in aneuploid, but not in diploid colorectal cancer cell lines, and correlates with numerical chromosomal aberrations. Genes Chromosomes Cancer. 2000 Feb;27(2):183-90. PMID: 10612807
Melcher R, Koehler S, Steinlein C, Schmid M, Mueller CR, Luehrs H, Menzel T, Scheppach W, Moerk H, Scheurlen M, Koehrle J, Al-Taie O. Spectral karyotype analysis of colon cancer cell lines of the tumor suppressor and mutator pathway. Cytogenet Genome Res. 2002;98(1):22-8.
Melcher R, Steinlein C, Feichtinger W, Muller CR, Menzel T, Luhrs H, Scheppach W, Schmid M. Spectral karyotyping of the human colon cancer cell lines SW480 and SW620. Cytogenet Cell Genet. 2000;88(1-2):145-52.
Chun YH, Kil JI, Suh YS, Kim SH, Kim H, Park SH. Characterization of chromosomal aberrations in human gastric carcinoma cell lines using chromosome painting. Cancer Genet Cytogenet. 2000 May;119(1):18-25.
Stamouli MI, Ferti AD, Panani AD, Raftakis J, Consoli C, Raptis SA, Young BD. Application of multiplex fluorescence in situ hybridization in the cytogenetic analysis of primary gastric carcinoma. Cancer Genet Cytogenet. 2002 May;135(1):23-7. PMID: 12072199
Ashman JN, Brigham J, Cowen ME, Bahia H, Greenman J, Lind M, Cawkwell L. Chromosomal alterations in small cell lung cancer revealed by multicolour fluorescence in situ hybridization. Int J Cancer. 2002;102(3):230-6. PMID: 1239764
Grigorova M, Lyman RC, Caldas C, Edwards PAW . Chromosome abnormalities in 10 lung cancer cell lines of the NCI-H series analyzed with spectral karyotyping. Cancer Genet Cytogenet 2005; 162, 1-9.
Luk C, Tsao MS, Bayani J, Shepherd F, Squire JA. Molecular cytogenetic analysis of non-small cell lung carcinoma by spectral karyotyping and comparative genomic hybridization. Cancer Genet Cytogenet. 2001 Mar;125(2):87-99. PMID: 1136905
Speicher MR, Petersen S, Uhrig S, Jentsch I, Fauth C, Eils R, Petersen I. Analysis of chromosomal alterations in non-small cell lung cancer by multiplex-FISH, comparative genomic hybridization, and multicolor bar coding. Lab Invest. 2000 Jul;80(7):1031-41
Rao PH, Harris CP, Yan Lu X, Li XN, Mok SC, Lau CC. Multicolor spectral karyotyping of serous ovarian adenocarcinoma. Genes Chromosomes Cancer. 2002 Feb;33(2):123-32.
Ghadimi BM, Schrock E, Walker RL, Wangsa D, Jauho A, Meltzer PS, Ried T. Specific chromosomal aberrations and amplification of the AIB1 nuclear receptor coactivator gene in pancreatic carcinomas. Am J Pathol. 1999 Feb;154(2):525-36. PMID: 10027410
Sirivatanauksorn V, Sirivatanauksorn Y, Gorman PA, Davidson JM, Sheer D, Moore PS, Scarpa A, Edwards PA, Lemoine NR. Non-random chromosomal rearrangements in pancreatic cancer cell lines identified by spectral karyotyping. Int J Cancer. 2001; 91(3):350-8. PMID: 11169959
Pan Y, Kytola S, Farnebo F, Wang N, Lui WO, Nupponen N, Isola J, Visakorpi T, Bergerheim US, Larsson C. Characterization of chromosomal abnormalities in prostate cancer cell lines by spectral karyotyping. Cytogenet Cell Genet. 1999;87(3-4):225-32. PMID: 10702678
Strefford JC, Lillington DM, Young BD, Oliver RT. The use of multicolor fluorescence technologies in the characterization of prostate carcinoma cell lines: a comparison of multiplex fluorescence in situ hybridization and spectral karyotyping data. Cancer Genet Cytogenet. 2001 Jan 15;124(2):112-21. PMID: 11172901
Aurich-Costa J, Vannier A, Gregoire E, Nowak F, Cherif D. IPM-FISH, a new M-FISH approach using IRS-PCR painting probes: application to the analysis of seven human prostate cell lines. Genes Chromosomes Cancer. 2001 Feb;30(2):143-6