Molecular Cytogenetics of Common Epithelial Cancers > Colon Carcinoma cell lines > C70

C70

Colon Cancer Cell Line

Description

More than tetraploid line. Derived in the Bodmer lab.

   
Notable Features

Large numbers of normal chromosomes. Suggests reduplication from hyperdiploid

   
Representative SKY Karyotype
   
   

127 (115–130), XXXXX, 1x4, der(1)t(1;5)(p12;p13)x2, 2x1, del(2)(p21), del(2)x4, 3x6, 4x2, der(4)del(4)(q31q35)t(4;18)(?p15;?)x2, 5x4, 6x3, 7x9, 8x5, 9x5, 10x4, der(10)t(3;10)(?;q23~24), 11x3, del(11)(?q23), der(11)t(11;11) x3, 12x6, der(12)t(12;22) t(12;22), 13x6, der(13)t(13;13)x2, 14x4, 15x6, 16x3, der(16)t(10;16)(q23~24;q24)x2, 17x2, der(17)t(6;17)(?q23;q24~25)x2, 18x4, 19x4, der(19)t(19;22)(p;q)x2, 20x9, 21x2, der(?)t(17;21)(q10;q10)x2, 22x3[12]/idem, +der(8)t(5;8)[2]

   
 
Additional Information  


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Colon Cancer Cell Lines