Molecular Cytogenetics of Common Epithelial Cancers > Breast Carcinoma cell lines > MT-3

MT-3

'Breast' Cancer Cell Line, actually colorectal

Description

Shown by SNP analysis* to be identical to colorectal line LS174T (*http://www.sanger.ac.uk/genetics/CGP/Genotyping/synlinestable.shtml)

Obtained from originators. (Hambly et al, 1997)

Almost normal karyotype with only changes trisomy 7 and iso13, like a typical microsatellite-unstable colorectal line. One X, suggesting male origin. Given that the other lines in this series, MT-1, MC4000 and MaTu are HeLa contaminants, the authenticity of this line was always in doubt.

   
Notable Features

   
Representative SKY Karyotype
   
   

46(36-47), X, +7, i(13)(q), -X [10]

   
 
Additional Information  


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