Molecular Cytogenetics of Common Epithelial Cancers > Breast Carcinoma cell lines > GI 101

GI 101

Breast Cancer Cell Line

Description

Near-normal karyotype, rather similar to simple colorectal cancer karyotypes. Obtained from Dr Mike O'Hare.

   
Notable Features

   
Representative SKY Karyotype
   
   

53 (51-54), XX, + iso(1), del(2), +6,+7,+8,+13, iso(14), iso(15),+16. One copy each of 5, 9 and 10 may be abnormal.

The 11;21 translocation in the metaphase shown was only present in one metaphase, and the apparent blue band across one chromosome 9 is a overlap with another chromosome.

   
 
Additional Information  


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FISH, SKY and CGH

Breast Cancer Cell Lines