Acknowledgement of source material
The text and figures here have been adapted with permission of the authors and
publisher from
"Reshaping antibodies for therapy"
Edward G. Routledge, Scott D. Gorman and Mike Clark,
in
Protein Engineering of Antibody Molecules for Prophylatic and Therapeutic
Applications in Man
pp.13-44 (1993)
edited by Mike Clark
publisher, Academic Titles, Nottingham, England
ISBN 1 874695 00 8
This book was originally published in 1993 but is now out of print. However the contents of this
chapter are still highly relevant to current strategies for reshaping antibodies. I have sought the
permission of my coauthors and the publisher to adapt the material for publication over the web. Please
note however that the material still remains copyright.
I have endeavoured not to introduce too many changes to the text except where necessary to facilitate the
delivery of the information in HTML or to make minor corrections and updates. Please address any comments
or corrections to me as given in the references below.
These pages were last updated on 11th June 1997
Please address any correspondence to Mike Clark mrc7@cam.ac.uk
Home page URL /~mrc7/