Mike Clark
"An antibody engineer who also enjoys the mountains."
mrc7@cam.ac.uk
Mike's home-page
© Mike Clark, PhD., Cambridge University, UK
Last updated on 12th July 2001
QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNYNQKFKD RFTISTDKSKSTAYLQMDSLRPEDTAVYYCARYYDDHYCLDYWGQGTPVTVSS
To be added
TFASTA translates and searches a DNA sequence data bank
version 3.2t07 August 17, 1999
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
/tmp/.fasta3-search-2008169: 98 aa
>OKT3Hh
vs V-Base Nucleic library
searching /data/V-Base/D_VBASE.txt library
searching /data/V-Base/JH_VBASE.txt library
searching /data/V-Base/JK_VBASE.txt library
searching /data/V-Base/JL_VBASE.txt library
searching /data/V-Base/VH_VBASE.txt library
searching /data/V-Base/VK_VBASE.txt library
searching /data/V-Base/VL_VBASE.txt library
167154 residues in 638 sequences
Expectation_n fit: rho(ln(x))= 67.1836+/- 0.012; mu= -205.1453+/- 0.559;
mean_var=10440.0651+/-8558.010, 0's: 1 Z-trim: 0 B-trim: 0 in 0/21
TFASTA (3.27 August, 1999) function [optimized, BL50 matrix (15:-5)] ktup: 2
join: 36, opt: 36, gap-pen: -16/ -2, width: 16 reg.-scaled
Scan time: 0.280
The best scores are: initn init1 opt z-sc E(637)
b25 ( 296) [1] 481 481 481 79.7 7.8
b52 ( 296) [1] 480 480 480 79.6 7.9
COS-8_hv3005f3-.. ( 296) [1] 480 480 480 79.6 7.9
b43 ( 296) [1] 480 480 480 79.6 7.9
b54-._hv3005b54 ( 296) [1] 480 480 480 79.6 7.9
hv3005_b1-.m... ( 296) [1] 480 480 480 79.6 7.9
b32e_b36m ( 296) [1] 480 480 480 79.6 7.9
b48 ( 296) [1] 480 480 480 79.6 7.9
DP-46_3d216-.. ( 296) [1] 480 480 480 79.6 7.9
VH3-8 ( 294) [1] 478 478 478 79.5 8.1
b13-._hv3019b13 ( 296) [1] 478 478 478 79.4 8.1
b26 ( 296) [1] 478 478 478 79.4 8.1
b28e ( 296) [1] 478 478 478 79.4 8.1
b37 ( 296) [1] 478 478 478 79.4 8.1
b18-._hv3019b18 ( 296) [1] 478 478 478 79.4 8.1
V3-30 ( 296) [1] 478 478 478 79.4 8.1
b29m ( 296) [1] 478 478 478 79.4 8.1
p2 ( 296) [1] 473 473 476 79.2 8.3
b28m ( 296) [1] 476 476 476 79.2 8.3
f7 ( 296) [1] 475 475 475 79.2 8.5
DP-49_1-9III... ( 296) [1] 471 471 474 79.1 8.6
b30 ( 296) [1] 473 473 473 79.0 8.7
DP-50_hv3019b9-.. ( 296) [1] 473 473 473 79.0 8.7
b29e ( 296) [1] 472 472 472 78.9 8.8
f3-.e ( 296) [1] 470 470 470 78.7 9
b32m ( 296) [1] 469 469 469 78.6 9.1
p6 ( 296) [1] 466 466 469 78.6 9.1
GL-SJ2e ( 294) [1] 468 468 468 78.5 9.2
COS-3_BHGH1 ( 296) [1] 464 464 467 78.4 9.3
DP-39_HC16-8-.. ( 296) [1] 461 461 466 78.3 9.5
V3-48_hv3d1-.. ( 296) [1] 463 463 465 78.2 9.6
DP-51 ( 296) [1] 463 463 465 78.2 9.6
COS-16 ( 298) [1] 458 458 463 77.9 9.9
VH26Rabbitts ( 296) [1] 457 457 462 77.9 9.9
COS-6_DA-8-.. ( 296) [1] 460 460 462 77.9 9.9
DP-53_hvm148-.. ( 296) [1] 460 460 462 77.9 9.9
H11Rechavi ( 296) [1] 459 459 461 77.8 10
DP-47_V3-23-.. ( 296) [1] 456 456 461 77.8 10
DP-77_WHG16 ( 296) [1] 458 458 460 77.7 10
V3-21 ( 296) [1] 458 458 460 77.7 10
V3-33 ( 296) [1] 460 460 460 77.7 10
DP-58_hv3d1EG ( 296) [1] 458 458 460 77.7 10
DP-31_V3-9P-.. ( 298) [1] 455 455 460 77.6 10
DP-40_HC16-9-.. ( 296) [1] 451 451 456 77.3 11
V3-64_YAC-6 ( 296) [1] 453 453 455 77.2 11
f2m ( 296) [1] 452 452 455 77.2 11
DP-35_V3-11-.. ( 296) [1] 455 455 455 77.2 11
DP-33_V3-43 ( 298) [1] 449 449 454 77.1 11
V3-49 ( 302) [1] 406 270 454 77.0 11
DP-7_21-2-.. ( 296) [1] 452 452 452 76.9 11
hv1f10t ( 296) [1] 452 452 452 76.9 11
HG3 ( 296) [1] 451 451 451 76.8 11
p1 ( 296) [1] 445 445 450 76.7 12
f1m_f2e ( 296) [1] 445 445 450 76.7 12
VHGL1-2 ( 296) [1] 449 449 449 76.6 12
DP-75_VI-2-.. ( 296) [1] 449 449 449 76.6 12
LSG12-1 ( 302) [1] 403 266 450 76.6 12
DP-34_DA-10 ( 302) [1] 417 269 450 76.6 12
VH26-3-7 ( 294) [1] 442 442 447 76.5 12
DP-87_HC16-13 ( 296) [1] 437 437 446 76.3 12
HHG4 ( 293) [1] 413 271 445 76.3 12
DP-32_V3-20 ( 296) [1] 441 441 443 76.0 13
DP-25_VI-3b ( 296) [1] 441 441 441 75.8 13
DP-45 ( 293) [1] 410 274 439 75.7 13
RR-VH1.1e ( 294) [1] 439 439 439 75.7 13
p9e ( 286) [1] 437 437 437 75.7 13
YAC-7_10M28-.. ( 296) [1] 439 439 439 75.6 13
DP-8 ( 296) [1] 439 439 439 75.6 13
VH3-11 ( 294) [1] 436 436 438 75.6 13
DP-54_V3-7-.. ( 296) [1] 436 436 438 75.5 13
8M27 ( 296) [1] 438 438 438 75.5 13
V35_VI-2b ( 296) [1] 436 436 436 75.3 14
4M28 ( 296) [1] 434 434 434 75.1 14
DP-1_HC15-1 ( 296) [1] 434 434 434 75.1 14
hv1263_3M28-.. ( 296) [1] 434 434 434 75.1 14
DP-44_HC16-10-.. ( 293) [1] 404 268 433 75.1 14
8-1B ( 293) [1] 400 251 432 75.0 14
YAC-5 ( 293) [1] 400 251 432 75.0 14
MTGLa ( 293) [1] 400 251 432 75.0 14
12M28 ( 296) [1] 432 432 432 74.9 14
V3-53 ( 293) [1] 399 250 431 74.9 14
RR-VH1.2 ( 294) [1] 431 431 431 74.9 15
DP-88_hv1051K-.. ( 296) [1] 431 431 431 74.8 15
DP-29_12-2 ( 302) [1] 404 263 431 74.7 15
1-1 ( 296) [1] 429 429 429 74.6 15
DP-4 ( 296) [1] 421 421 429 74.6 15
7-2 ( 296) [1] 421 421 429 74.6 15
DP-42 ( 293) [1] 396 247 428 74.6 15
HA2 ( 296) [1] 428 428 428 74.6 15
6M27 ( 296) [1] 428 428 428 74.6 15
LSG4-1 ( 302) [1] 407 254 429 74.5 15
YAC-9_COS-27-.. ( 302) [1] 395 256 428 74.4 15
2M27_11M27-.. ( 296) [1] 426 426 426 74.4 16
VHGL1-8 ( 296) [1] 426 426 426 74.4 16
DP-10_hv1051-.. ( 296) [1] 426 426 426 74.4 16
DP-48_13-2 ( 293) [1] 398 271 425 74.3 16
VHGL1-9 ( 296) [1] 425 425 425 74.3 16
LSG6-1 ( 302) [1] 388 256 426 74.2 16
VHVBLK32 ( 294) [1] 421 421 423 74.1 16
VI-4-1b ( 296) [1] 423 423 423 74.1 16
>>b25 (296 aa)
Frame: 1 initn: 481 init1: 481 opt: 481 Z-score: 79.7 expect() 7.8
73.469% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::::::::::::::::::: :::: :: :.::::::::::::::.. :. . . :
b25 QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYAMHWVRQAPGKGLEWVAVISYDGSNKYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
... : ::::: :.::.: ::::.::: ::::::::::
b25 TDSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>b52 (296 aa)
Frame: 1 initn: 480 init1: 480 opt: 480 Z-score: 79.6 expect() 7.9
73.469% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::::::::::::::::::: :::: :: :.::::::::::::::.. :. . . :
b52 QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYAMHWVRQAPGKGLEWVAVISYDGSNKYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: ::::.::: ::::::::::
b52 ADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>COS-8_hv3005f3-.. (296 aa)
Frame: 1 initn: 480 init1: 480 opt: 480 Z-score: 79.6 expect() 7.9
73.469% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::::::::::::::::::: :::: :: :.::::::::::::::.. :. . . :
COS-8_ QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYAMHWVRQAPGKGLEWVAVISYDGSNKYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: ::::.::: ::::::::::
COS-8_ ADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>b43 (296 aa)
Frame: 1 initn: 480 init1: 480 opt: 480 Z-score: 79.6 expect() 7.9
73.469% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::::::::::::::::::: :::: :: :.::::::::::::::.. :. . . :
b43 QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYAMHWVRQAPGKGLEWVAVISYDGSNKYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: ::::.::: ::::::::::
b43 ADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>b54-._hv3005b54 (296 aa)
Frame: 1 initn: 480 init1: 480 opt: 480 Z-score: 79.6 expect() 7.9
73.469% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::::::::::::::::::: :::: :: :.::::::::::::::.. :. . . :
b54-._ QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYAMHWVRQAPGKGLEWVAVISYDGSNKYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: ::::.::: ::::::::::
b54-._ ADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>hv3005_b1-.m... (296 aa)
Frame: 1 initn: 480 init1: 480 opt: 480 Z-score: 79.6 expect() 7.9
73.469% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::::::::::::::::::: :::: :: :.::::::::::::::.. :. . . :
hv3005 QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYAMHWVRQAPGKGLEWVAVISYDGSNKYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: ::::.::: ::::::::::
hv3005 ADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>b32e_b36m (296 aa)
Frame: 1 initn: 480 init1: 480 opt: 480 Z-score: 79.6 expect() 7.9
73.469% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::::::::::::::::::: :::: :: :.::::::::::::::.. :. . . :
b32e_b QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYAMHWVRQAPGKGLEWVAVISYDGSNKYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: ::::.::: ::::::::::
b32e_b ADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>b48 (296 aa)
Frame: 1 initn: 480 init1: 480 opt: 480 Z-score: 79.6 expect() 7.9
73.469% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::::::::::::::::::: :::: :: :.::::::::::::::.. :. . . :
b48 QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYAMHWVRQAPGKGLEWVAVISYDGSNKYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: ::::.::: ::::::::::
b48 ADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>DP-46_3d216-.. (296 aa)
Frame: 1 initn: 480 init1: 480 opt: 480 Z-score: 79.6 expect() 7.9
73.469% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::::::::::::::::::: :::: :: :.::::::::::::::.. :. . . :
DP-46_ QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYAMHWVRQAPGKGLEWVAVISYDGSNKYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: ::::.::: ::::::::::
DP-46_ ADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>VH3-8 (294 aa)
Frame: 1 initn: 478 init1: 478 opt: 478 Z-score: 79.5 expect() 8.1
70.408% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
::::.:::::.:.:: :::::: :::: :: : : :.::::::::::..::. : .::::
VH3-8 QVQLLESGGGLVKPGGSLRLSCAASGFTFSDYYMSWIRQAPGKGLEWVSYISSSSSYTNY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :..:.. ::::.::: ::::::::::
VH3-8 ADSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>b13-._hv3019b13 (296 aa)
Frame: 1 initn: 478 init1: 478 opt: 478 Z-score: 79.4 expect() 8.1
73.469% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::::::::::::::::::: :::: :: : ::::::::::::::.. :. . . :
b13-._ QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYGMHWVRQAPGKGLEWVAVISYDGSNKYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: ::::.::: ::::::::::
b13-._ ADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>b26 (296 aa)
Frame: 1 initn: 478 init1: 478 opt: 478 Z-score: 79.4 expect() 8.1
73.469% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::::::::::::::::::: :::: :: : ::::::::::::::.. :. . . :
b26 QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYGMHWVRQAPGKGLEWVAVISYDGSNKYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: ::::.::: ::::::::::
b26 ADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>b28e (296 aa)
Frame: 1 initn: 478 init1: 478 opt: 478 Z-score: 79.4 expect() 8.1
73.469% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::::::::::::::::::: :::: :: : ::::::::::::::.. :. . . :
b28e QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYGMHWVRQAPGKGLEWVAVISYDGSNKYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: ::::.::: ::::::::::
b28e ADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>b37 (296 aa)
Frame: 1 initn: 478 init1: 478 opt: 478 Z-score: 79.4 expect() 8.1
73.469% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::::::::::::::::::: :::: :: :.::::::::::::::.. :. . . :
b37 QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYAMHWVRQAPGKGLEWVAVISYDGSNKYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: ::::.::: ::::::::::
b37 ADSVKGRFTISRDNSKNTLYLQMSSLRAEDTAVYYCAR
190 220 250 280
>>b18-._hv3019b18 (296 aa)
Frame: 1 initn: 478 init1: 478 opt: 478 Z-score: 79.4 expect() 8.1
73.469% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::::::::::::::::::: :::: :: : ::::::::::::::.. :. . . :
b18-._ QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYGMHWVRQAPGKGLEWVAVISYDGSNKYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: ::::.::: ::::::::::
b18-._ ADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>V3-30 (296 aa)
Frame: 1 initn: 478 init1: 478 opt: 478 Z-score: 79.4 expect() 8.1
73.469% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::::::::::::::::::: :::: :: : ::::::::::::::.. :. . . :
V3-30 QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYGMHWVRQAPGKGLEWVAVISYDGSNKYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: ::::.::: ::::::::::
V3-30 ADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>b29m (296 aa)
Frame: 1 initn: 478 init1: 478 opt: 478 Z-score: 79.4 expect() 8.1
73.469% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::::::::::::::::::: :::: :: : ::::::::::::::.. :. . . :
b29m QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYGMHWVRQAPGKGLEWVAVISYDGSNKYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: ::::.::: ::::::::::
b29m ADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>p2 (296 aa)
Frame: 1 initn: 473 init1: 473 opt: 476 Z-score: 79.2 expect() 8.3
72.449% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::::::::::::::::::: :::: :: :.::::::::::::::.. :. . . :
p2 QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYAMHWVRQAPGKGLEWVAVISYDGSNKYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: ::::.::: :::::::::.
p2 ADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAK
190 220 250 280
>>b28m (296 aa)
Frame: 1 initn: 476 init1: 476 opt: 476 Z-score: 79.2 expect() 8.3
73.469% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::::::::::::::::::: :::: :: : ::::::::::::::.. : . . :
b28m QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYGMHWVRQAPGKGLEWVAVIXYDGSNKYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: ::::.::: ::::::::::
b28m ADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>f7 (296 aa)
Frame: 1 initn: 475 init1: 475 opt: 475 Z-score: 79.2 expect() 8.5
72.449% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::::::::::::::::::: :::: :: :.::::::::::::::.. :. . . :
f7 QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYAMHWVRQAPGKGLEWVAVISYDGSNKYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::.:: :.::.: ::::.::: ::::::::::
f7 ADSVKGRFAISRDNSKNTLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>DP-49_1-9III... (296 aa)
Frame: 1 initn: 471 init1: 471 opt: 474 Z-score: 79.1 expect() 8.6
72.449% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::::::::::::::::::: :::: :: : ::::::::::::::.. :. . . :
DP-49_ QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYGMHWVRQAPGKGLEWVAVISYDGSNKYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: ::::.::: :::::::::.
DP-49_ ADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAK
190 220 250 280
>>b30 (296 aa)
Frame: 1 initn: 473 init1: 473 opt: 473 Z-score: 79.0 expect() 8.7
73.469% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::::::::::::::::::: :::: :: : ::::::::::::::.. : . . :
b30 QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYGMHWVRQAPGKGLEWVAVIWYDGSNKYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: ::::.::: ::::::::::
b30 ADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>DP-50_hv3019b9-.. (296 aa)
Frame: 1 initn: 473 init1: 473 opt: 473 Z-score: 79.0 expect() 8.7
73.469% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::::::::::::::::::: :::: :: : ::::::::::::::.. : . . :
DP-50_ QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYGMHWVRQAPGKGLEWVAVIWYDGSNKYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: ::::.::: ::::::::::
DP-50_ ADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>b29e (296 aa)
Frame: 1 initn: 472 init1: 472 opt: 472 Z-score: 78.9 expect() 8.8
72.449% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::::::::::::::::::: :::: :: : ::::::::::::::.. :. . . :
b29e QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYGMHWVRQAPGKGLEWVAVISYDGSNKYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::. ::::.::: ::::::::::
b29e ADSVKGRFTISRDNSKNRLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>f3-.e (296 aa)
Frame: 1 initn: 470 init1: 470 opt: 470 Z-score: 78.7 expect() 9
72.449% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
::::::::::.:::: ::::::.:::: :: :.:::::::::::::... :. . : : :
f3-.e QVQLVESGGGLVQPGGSLRLSCSASGFTFSSYAMHWVRQAPGKGLEYVSAISSNGGSTYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: ::::.::: ::::::::::
f3-.e ADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>b32m (296 aa)
Frame: 1 initn: 469 init1: 469 opt: 469 Z-score: 78.6 expect() 9.1
72.449% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::::::::::::::::::: :::: :: : ::::::::::::::.. :. . . :
b32m QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYGMHWVRQAPGKGLEWVAVISYDGSNKYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: ::::.::: : ::::::::
b32m ADSVKGRFTISRDNSKNTLYLQMNSLRAEGTAVYYCAR
190 220 250 280
>>p6 (296 aa)
Frame: 1 initn: 466 init1: 466 opt: 469 Z-score: 78.6 expect() 9.1
72.449% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::::::::::::::::::: :::: :: : ::::::::::::::.. : . . :
p6 QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYGMHWVRQAPGKGLEWVAVIWYDGSNKYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: ::::.::: :::::::::.
p6 ADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAK
190 220 250 280
>>GL-SJ2e (294 aa)
Frame: 1 initn: 468 init1: 468 opt: 468 Z-score: 78.5 expect() 9.2
71.429% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::.:::::::::::::::: ::.: :: :.::::::::::::::.. :. . . :
GL-SJ2 QVQLVDSGGGVVQPGRSLRLSCAASAFTFSSYAMHWVRQAPGKGLEWVAVISYDGSNKYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: ::::.::: ::::::::::
GL-SJ2 ADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>COS-3_BHGH1 (296 aa)
Frame: 1 initn: 464 init1: 464 opt: 467 Z-score: 78.4 expect() 9.3
71.429% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
::::::::::::::: :::::: :::: :: : ::::::::::::::...: . . :
COS-3_ QVQLVESGGGVVQPGGSLRLSCAASGFTFSSYGMHWVRQAPGKGLEWVAFIRYDGSNKYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: ::::.::: :::::::::.
COS-3_ ADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAK
190 220 250 280
>>DP-39_HC16-8-.. (296 aa)
Frame: 1 initn: 461 init1: 461 opt: 466 Z-score: 78.3 expect() 9.5
68.367% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
.:::::::::.:::: :::::: :::: :: . : ::::::::::::..::. . :::::
DP-39_ EVQLVESGGGLVQPGGSLRLSCPASGFTFSNHYMSWVRQAPGKGLEWVSYISGDSGYTNY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :..... ::::.::: ::::::::..
DP-39_ ADSVKGRFTISRDNANNSPYLQMNSLRAEDTAVYYCVK
190 220 250 280
>>V3-48_hv3d1-.. (296 aa)
Frame: 1 initn: 463 init1: 463 opt: 465 Z-score: 78.2 expect() 9.6
69.388% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
.:::::::::.:::: :::::: :::: :: :.:.::::::::::::..::. : . :
V3-48_ EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYSMNWVRQAPGKGLEWVSYISSSSSTIYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :..:.. ::::.::: ::::::::::
V3-48_ ADSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>DP-51 (296 aa)
Frame: 1 initn: 463 init1: 463 opt: 465 Z-score: 78.2 expect() 9.6
69.388% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
.:::::::::.:::: :::::: :::: :: :.:.::::::::::::..::. : . :
DP-51 EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYSMNWVRQAPGKGLEWVSYISSSSSTIYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :..:.. ::::.::: ::::::::::
DP-51 ADSVKGRFTISRDNAKNSLYLQMNSLRDEDTAVYYCAR
190 220 250 280
>>COS-16 (298 aa)
Frame: 1 initn: 458 init1: 458 opt: 463 Z-score: 77.9 expect() 9.9
69.388% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
.:::::::::::::: :::::: :::: :. :.::::::::::::::.. :. . : : :
COS-16 EVQLVESGGGVVQPGGSLRLSCAASGFTFDDYAMHWVRQAPGKGLEWVSLISGDGGSTYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.. ::::.::: ::::.::::.
COS-16 ADSVKGRFTISRDNSKNSLYLQMNSLRTEDTALYYCAKD
190 220 250 280
>>VH26Rabbitts (296 aa)
Frame: 1 initn: 457 init1: 457 opt: 462 Z-score: 77.9 expect() 9.9
70.408% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
.:::.:::::.:::: :::::: :::: :: :.: ::::::::::::.. :. : : : :
VH26Ra EVQLLESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
... : ::::: :.::.: ::::.::: :::::::::.
VH26Ra GDSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAK
190 220 250 280
>>COS-6_DA-8-.. (296 aa)
Frame: 1 initn: 460 init1: 460 opt: 462 Z-score: 77.9 expect() 9.9
70.408% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
.:::::::::.:::: :::::: :::: :: : :::::::::::: :.. :: . . :.:
COS-6_ EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYWMHWVRQAPGKGLVWVSRINSDGSSTSY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :..:.: ::::.::: ::::::::::
COS-6_ ADSVKGRFTISRDNAKNTLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>DP-53_hvm148-.. (296 aa)
Frame: 1 initn: 460 init1: 460 opt: 462 Z-score: 77.9 expect() 9.9
70.408% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
.:::::::::.:::: :::::: :::: :: : :::::::::::: :.. :: . . :.:
DP-53_ EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYWMHWVRQAPGKGLVWVSRINSDGSSTSY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :..:.: ::::.::: ::::::::::
DP-53_ ADSVKGRFTISRDNAKNTLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>H11Rechavi (296 aa)
Frame: 1 initn: 459 init1: 459 opt: 461 Z-score: 77.8 expect() 10
70.408% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
.:::::::::.:::: :::::: :::: :: : :::::::::::: :.. :: . . :.:
H11Rec EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYWMHWVRQAPGKGLVWVSRINSDGSSTTY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :..:.: ::::.::: ::::::::::
H11Rec ADSVKGRFTISRDNAKNTLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>DP-47_V3-23-.. (296 aa)
Frame: 1 initn: 456 init1: 456 opt: 461 Z-score: 77.8 expect() 10
70.408% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
.:::.:::::.:::: :::::: :::: :: :.: ::::::::::::.. :. : : : :
DP-47_ EVQLLESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSAISGSGGSTYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: ::::.::: :::::::::.
DP-47_ ADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAK
190 220 250 280
>>DP-77_WHG16 (296 aa)
Frame: 1 initn: 458 init1: 458 opt: 460 Z-score: 77.7 expect() 10
68.367% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
.:::::::::.:.:: :::::: :::: :: :.:.::::::::::::.. :. : .: :
DP-77_ EVQLVESGGGLVKPGGSLRLSCAASGFTFSSYSMNWVRQAPGKGLEWVSSISSSSSYIYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :..:.. ::::.::: ::::::::::
DP-77_ ADSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>V3-21 (296 aa)
Frame: 1 initn: 458 init1: 458 opt: 460 Z-score: 77.7 expect() 10
68.367% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
.:::::::::.:.:: :::::: :::: :: :.:.::::::::::::.. :. : .: :
V3-21 EVQLVESGGGLVKPGGSLRLSCAASGFTFSSYSMNWVRQAPGKGLEWVSSISSSSSYIYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :..:.. ::::.::: ::::::::::
V3-21 ADSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>V3-33 (296 aa)
Frame: 1 initn: 460 init1: 460 opt: 460 Z-score: 77.7 expect() 10
71.429% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::::::::::::::::::: :::: :: : ::::::::::::::.. : . . :
V3-33 QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYGMHWVRQAPGKGLEWVAVIWYDGSNKYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.: .: .:::.::: ::::::::::
V3-33 ADSAKGRFTISRDNSTNTLFLQMNSLRAEDTAVYYCAR
190 220 250 280
>>DP-58_hv3d1EG (296 aa)
Frame: 1 initn: 458 init1: 458 opt: 460 Z-score: 77.7 expect() 10
69.388% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
.:::::::::.:::: :::::: :::: :: : :.::::::::::::..::. : . :
DP-58_ EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYEMNWVRQAPGKGLEWVSYISSSGSTIYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :..:.. ::::.::: ::::::::::
DP-58_ ADSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>DP-31_V3-9P-.. (298 aa)
Frame: 1 initn: 455 init1: 455 opt: 460 Z-score: 77.6 expect() 10
67.347% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
.:::::::::.::::::::::: :::: :. :.::::::::::::::.. :. . : .:
DP-31_ EVQLVESGGGLVQPGRSLRLSCAASGFTFDDYAMHWVRQAPGKGLEWVSGISWNSGSIGY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :..:.. ::::.::: ::::.::::.
DP-31_ ADSVKGRFTISRDNAKNSLYLQMNSLRAEDTALYYCAKD
190 220 250 280
>>DP-40_HC16-9-.. (296 aa)
Frame: 1 initn: 451 init1: 451 opt: 456 Z-score: 77.3 expect() 11
67.347% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
.:::::::::.:::: :::::: :::: :: . ::::::::::::..: . . :::::
DP-40_ EVQLVESGGGLVQPGGSLRLSCAASGFTFSNHYTSWVRQAPGKGLEWVSYSSGNSGYTNY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :..:.. ::::.::: ::::::::..
DP-40_ ADSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCVK
190 220 250 280
>>V3-64_YAC-6 (296 aa)
Frame: 1 initn: 453 init1: 453 opt: 455 Z-score: 77.2 expect() 11
70.408% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
.:::::::::.:::: :::::: :::: :: :.:::::::::::::... :. . : : :
V3-64_ EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYAMHWVRQAPGKGLEYVSAISSNGGSTYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: :::: ::: :: :::::::
V3-64_ ANSVKGRFTISRDNSKNTLYLQMGSLRAEDMAVYYCAR
190 220 250 280
>>f2m (296 aa)
Frame: 1 initn: 452 init1: 452 opt: 455 Z-score: 77.2 expect() 11
69.388% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
::::::::::.:::: ::::::.:::: :: :.:::::::::::::... :. . : : :
f2m QVQLVESGGGLVQPGGSLRLSCSASGFTFSSYAMHWVRQAPGKGLEYVSAISSNGGSTYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: :.::.::: ::::::::..
f2m ADSVKGRFTISRDNSKNTLYVQMSSLRAEDTAVYYCVK
190 220 250 280
>>DP-35_V3-11-.. (296 aa)
Frame: 1 initn: 455 init1: 455 opt: 455 Z-score: 77.2 expect() 11
68.367% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
::::::::::.:.:: :::::: :::: :: : : :.::::::::::..::. : . :
DP-35_ QVQLVESGGGLVKPGGSLRLSCAASGFTFSDYYMSWIRQAPGKGLEWVSYISSSGSTIYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :..:.. ::::.::: ::::::::::
DP-35_ ADSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>DP-33_V3-43 (298 aa)
Frame: 1 initn: 449 init1: 449 opt: 454 Z-score: 77.1 expect() 11
69.388% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
.:::::::: ::::: :::::: :::: :. ::::::::::::::::.. :. . : : :
DP-33_ EVQLVESGGVVVQPGGSLRLSCAASGFTFDDYTMHWVRQAPGKGLEWVSLISWDGGSTYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.. ::::.::: ::::.::::.
DP-33_ ADSVKGRFTISRDNSKNSLYLQMNSLRTEDTALYYCAKD
190 220 250 280
>>V3-49 (302 aa)
Frame: 1 initn: 406 init1: 270 opt: 454 Z-score: 77.0 expect() 11
69.000% identity in 100 aa overlap (1-98:1-300)
10 20 30 40 50
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSR--GYT
.:::::::::.::::::::::: :::: :. :.: : ::::::::::.:.: . : :
V3-49 EVQLVESGGGLVQPGRSLRLSCTASGFTFGDYAMSWFRQAPGKGLEWVGFIRSKAYGGTT
10 40 70 100 130 160
60 70 80 90
OKT3Hh NYNQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.:. . : ::::: : ::: :::::.::. ::::::::.:
V3-49 EYTASVKGRFTISRDGSKSIAYLQMNSLKTEDTAVYYCTR
190 220 250 280
>>DP-7_21-2-.. (296 aa)
Frame: 1 initn: 452 init1: 452 opt: 452 Z-score: 76.9 expect() 11
64.286% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::.::. : .:: :...::::::. :. : :::::::::.::::.: :::: : :.:
DP-7_2 QVQLVQSGAEVKKPGASVKVSCKASGYTFTSYYMHWVRQAPGQGLEWMGIINPSGGSTSY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
:::. : :.. : : ::.:....::: ::::::::::
DP-7_2 AQKFQGRVTMTRDTSTSTVYMELSSLRSEDTAVYYCAR
190 220 250 280
>>hv1f10t (296 aa)
Frame: 1 initn: 452 init1: 452 opt: 452 Z-score: 76.9 expect() 11
64.286% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::.::. : .:: :...::::::. :. : :::::::::.::::.: :::: : :.:
hv1f10 QVQLVQSGAEVKKPGASVKVSCKASGYTFTSYYMHWVRQAPGQGLEWMGIINPSGGSTSY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
:::. : :.. : : ::.:....::: ::::::::::
hv1f10 AQKFQGRVTMTRDTSTSTVYMELSSLRSEDTAVYYCAR
190 220 250 280
>>HG3 (296 aa)
Frame: 1 initn: 451 init1: 451 opt: 451 Z-score: 76.8 expect() 11
64.286% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::.::. : .:: :...::::::. :. : :::::::::.::::.: :::: : :.:
HG3 QVQLVQSGAEVKKPGASVKVSCKASGYTFNSYYMHWVRQAPGQGLEWMGIINPSGGSTSY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
:::. : :.. : : ::.:....::: ::::::::::
HG3 AQKFQGRVTMTRDTSTSTVYMELSSLRSEDTAVYYCAR
190 220 250 280
>>p1 (296 aa)
Frame: 1 initn: 445 init1: 445 opt: 450 Z-score: 76.7 expect() 12
68.367% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
.:::::::::.:::: ::::::.:::: :: :.:::::::::::::... :. . : : :
p1 EVQLVESGGGLVQPGGSLRLSCSASGFTFSSYAMHWVRQAPGKGLEYVSAISSNGGSTYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: :.::.::: ::::::::..
p1 ADSVKGRFTISRDNSKNTLYVQMSSLRAEDTAVYYCVK
190 220 250 280
>>f1m_f2e (296 aa)
Frame: 1 initn: 445 init1: 445 opt: 450 Z-score: 76.7 expect() 12
68.367% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
.:::::::::.:::: ::::::.:::: :: :.:::::::::::::... :. . : : :
f1m_f2 EVQLVESGGGLVQPGGSLRLSCSASGFTFSSYAMHWVRQAPGKGLEYVSAISSNGGSTYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: :.::.::: ::::::::..
f1m_f2 ADSVKGRFTISRDNSKNTLYVQMSSLRAEDTAVYYCVK
190 220 250 280
>>VHGL1-2 (296 aa)
Frame: 1 initn: 449 init1: 449 opt: 449 Z-score: 76.6 expect() 12
63.265% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::.::. : .:: :...::::::. :. : :::::::::.::::.:.:::. : :::
VHGL1- QVQLVQSGAEVKKPGASVKVSCKASGYTFTSYYMHWVRQAPGQGLEWMGWINPNSGGTNY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
:::. : :.. : : ::::.... :: .:::::::::
VHGL1- AQKFQGRVTMTRDTSISTAYVELSRLRSDDTAVYYCAR
190 220 250 280
>>DP-75_VI-2-.. (296 aa)
Frame: 1 initn: 449 init1: 449 opt: 449 Z-score: 76.6 expect() 12
63.265% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::.::. : .:: :...::::::. :. : :::::::::.::::.:.:::. : :::
DP-75_ QVQLVQSGAEVKKPGASVKVSCKASGYTFTGYYMHWVRQAPGQGLEWMGWINPNSGGTNY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
:::. : :.. : : ::::.... :: .:::::::::
DP-75_ AQKFQGRVTMTRDTSISTAYMELSRLRSDDTAVYYCAR
190 220 250 280
>>LSG12-1 (302 aa)
Frame: 1 initn: 403 init1: 266 opt: 450 Z-score: 76.6 expect() 12
69.000% identity in 100 aa overlap (1-98:1-300)
10 20 30 40 50
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSR--GYT
.:::::::::.:::: :::::: :::: :. : : ::::::::::::.:.: . : :
LSG12- EVQLVESGGGLVQPGPSLRLSCTASGFTFGYYPMSWVRQAPGKGLEWVGFIRSKAYGGTT
10 40 70 100 130 160
60 70 80 90
OKT3Hh NYNQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.: . : ::::: : ::: :::::.::. ::::::::.:
LSG12- EYAASVKGRFTISRDDSKSIAYLQMNSLKTEDTAVYYCTR
190 220 250 280
>>DP-34_DA-10 (302 aa)
Frame: 1 initn: 417 init1: 269 opt: 450 Z-score: 76.6 expect() 12
70.000% identity in 100 aa overlap (1-98:1-300)
10 20 30 40 50
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYI--NPSRGYT
.:::::::::.:::: :::::: :::: :: : : ::::::::::::.:.: . . : :
DP-34_ EVQLVESGGGLVQPGGSLRLSCAASGFTFSDYYMSWVRQAPGKGLEWVGFIRNKANGGTT
10 40 70 100 130 160
60 70 80 90
OKT3Hh NYNQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
. . . : ::::: : ::: .::::.::: ::::::::::
DP-34_ EXTTSVKGRFTISRDDSKSITYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>VH26-3-7 (294 aa)
Frame: 1 initn: 442 init1: 442 opt: 447 Z-score: 76.5 expect() 12
68.367% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
.:::.:::::.:::: :::::: :::: :: :.: ::::::::::::.. : . . : :
VH26-3 EVQLLESGGGLVQPGGSLRLSCAASGFTFSSYAMSWVRQAPGKGLEWVSVIYSGGSSTYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: ::::.::: :::::::::.
VH26-3 ADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAK
190 220 250 280
>>DP-87_HC16-13 (296 aa)
Frame: 1 initn: 437 init1: 437 opt: 446 Z-score: 76.3 expect() 12
67.347% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
.:::::::::.:::: :::::: :::: :: : :::::::::::: :.. :: . . :.:
DP-87_ EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYWMHWVRQAPGKGLVWVSRINSDGSSTSY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
...: .:::: :..:.: ::::.::: :: :::::.:
DP-87_ ADSMKGQFTISRDNAKNTLYLQMNSLRAEDMAVYYCTR
190 220 250 280
>>HHG4 (293 aa)
Frame: 1 initn: 413 init1: 271 opt: 445 Z-score: 76.3 expect() 12
68.367% identity in 98 aa overlap (1-98:1-291)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
.:::::::::.:.:: :::::: :::: :: :.:.::::::::::::.. :. : .: :
HHG4 EVQLVESGGGLVKPGGSLRLSCAASGFTFSSYSMNWVRQAPGKGLEWVSSIS-SSSYIYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :..:.. ::::.::: ::::::::::
HHG4 ADSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>DP-32_V3-20 (296 aa)
Frame: 1 initn: 441 init1: 441 opt: 443 Z-score: 76.0 expect() 13
67.347% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
.:::::::::::.:: :::::: :::: :. : : ::::::::::::.. :: . : :.:
DP-32_ EVQLVESGGGVVRPGGSLRLSCAASGFTFDDYGMSWVRQAPGKGLEWVSGINWNGGSTGY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :..:.. ::::.::: ::::.:.:::
DP-32_ ADSVKGRFTISRDNAKNSLYLQMNSLRAEDTALYHCAR
190 220 250 280
>>DP-25_VI-3b (296 aa)
Frame: 1 initn: 441 init1: 441 opt: 441 Z-score: 75.8 expect() 13
63.265% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::.::. : .:: :...::::::. :. :.:::::::::. :::.:.:: . : :.:
DP-25_ QVQLVQSGAEVKKPGASVKVSCKASGYTFTSYAMHWVRQAPGQRLEWMGWINAGNGNTKY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.:::. : ::. : : ::::....::: ::::::::::
DP-25_ SQKFQGRVTITRDTSASTAYMELSSLRSEDTAVYYCAR
190 220 250 280
>>DP-45 (293 aa)
Frame: 1 initn: 410 init1: 274 opt: 439 Z-score: 75.7 expect() 13
67.347% identity in 98 aa overlap (1-98:1-291)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
.::::.::::.:::: :::::: .::: :: :.::::::::::::::.. :. . : : :
DP-45 EVQLVQSGGGLVQPGGSLRLSCAGSGFTFSSYAMHWVRQAPGKGLEWVSAIG-TGGGTYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :..:.. ::::.::: :: :::::::
DP-45 ADSVKGRFTISRDNAKNSLYLQMNSLRAEDMAVYYCAR
190 220 250 280
>>RR-VH1.1e (294 aa)
Frame: 1 initn: 439 init1: 439 opt: 439 Z-score: 75.7 expect() 13
65.306% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::.::. : .:: :...:::::: :: ::. :::::::.::::.: : : : .::
RR-VH1 QVQLVQSGAEVKKPGSSVKVSCKASGGTFSSYTISWVRQAPGQGLEWMGRIIPILGIANY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
:::. : ::..::: ::::....::: ::::::::::
RR-VH1 AQKFQGRVTITADKSTSTAYMELSSLRSEDTAVYYCAR
190 220 250 280
>>p9e (286 aa)
Frame: 1 initn: 437 init1: 437 opt: 437 Z-score: 75.7 expect() 13
72.043% identity in 93 aa overlap (1-93:1-279)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::::::::::::::::::: :::: :: : ::::::::::::::.. :. . . :
p9e QVQLVESGGGVVQPGRSLRLSCAASGFTFSSYGMHWVRQAPGKGLEWVAVISYDGSNKYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: ::::.::: :::::
p9e ADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVRK
190 220 250 280
>>YAC-7_10M28-.. (296 aa)
Frame: 1 initn: 439 init1: 439 opt: 439 Z-score: 75.6 expect() 13
65.306% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::.::. : .:: :...:::::: :: ::. :::::::.::::.: : : : .::
YAC-7_ QVQLVQSGAEVKKPGSSVKVSCKASGGTFSSYTISWVRQAPGQGLEWMGRIIPILGIANY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
:::. : ::..::: ::::....::: ::::::::::
YAC-7_ AQKFQGRVTITADKSTSTAYMELSSLRSEDTAVYYCAR
190 220 250 280
>>DP-8 (296 aa)
Frame: 1 initn: 439 init1: 439 opt: 439 Z-score: 75.6 expect() 13
62.245% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::.::. : .:: :...::::::. :. : :::::::::.::::.:.:::. : :::
DP-8 QVQLVQSGAEVKKPGASVKVSCKASGYTFTGYYMHWVRQAPGQGLEWMGWINPNSGGTNY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
:::. :.. : : ::::.... :: .:::::::::
DP-8 AQKFQGWVTMTRDTSISTAYMELSRLRSDDTAVYYCAR
190 220 250 280
>>VH3-11 (294 aa)
Frame: 1 initn: 436 init1: 436 opt: 438 Z-score: 75.6 expect() 13
67.347% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
.:::::::::.:::: :::::: :::: :: : : ::::::::::::.. :. . . :
VH3-11 EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYWMSWVRQAPGKGLEWVANIKQDGSEKYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :..:.. ::::.::: ::::::::::
VH3-11 VDSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>DP-54_V3-7-.. (296 aa)
Frame: 1 initn: 436 init1: 436 opt: 438 Z-score: 75.5 expect() 13
67.347% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
.:::::::::.:::: :::::: :::: :: : : ::::::::::::.. :. . . :
DP-54_ EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYWMSWVRQAPGKGLEWVANIKQDGSEKYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :..:.. ::::.::: ::::::::::
DP-54_ VDSVKGRFTISRDNAKNSLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>8M27 (296 aa)
Frame: 1 initn: 438 init1: 438 opt: 438 Z-score: 75.5 expect() 13
65.306% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::.::. : .:: :...:::::: :: ::. :::::::.::::.: : : : .::
8M27 QVQLVQSGAEVKKPGSSVKVSCKASGGTFSSYTISWVRQAPGQGLEWMGRIIPILGTANY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
:::. : ::..::: ::::....::: ::::::::::
8M27 AQKFQGRVTITADKSTSTAYMELSSLRSEDTAVYYCAR
190 220 250 280
>>V35_VI-2b (296 aa)
Frame: 1 initn: 436 init1: 436 opt: 436 Z-score: 75.3 expect() 14
62.245% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::.::. : .:: :...::::::. :. : :::::::::.::::.: :::. : :::
V35_VI QVQLVQSGAEVKKPGASVKVSCKASGYTFTGYYMHWVRQAPGQGLEWMGRINPNSGGTNY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
:::. : : . : : ::::.... :: .::.::::::
V35_VI AQKFQGRVTSTRDTSISTAYMELSRLRSDDTVVYYCAR
190 220 250 280
>>4M28 (296 aa)
Frame: 1 initn: 434 init1: 434 opt: 434 Z-score: 75.1 expect() 14
64.286% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::.::. : .:: :...:::::: :: :.. :::::::.::::.: : : : .::
4M28 QVQLVQSGAEVKKPGSSVKVSCKASGGTFSSYAISWVRQAPGQGLEWMGRIIPILGIANY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
:::. : ::..::: ::::....::: ::::::::::
4M28 AQKFQGRVTITADKSTSTAYMELSSLRSEDTAVYYCAR
190 220 250 280
>>DP-1_HC15-1 (296 aa)
Frame: 1 initn: 434 init1: 434 opt: 434 Z-score: 75.1 expect() 14
63.265% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::.::. : .:: :...::::::.::. : :::::::::. : :.: :::. : :::
DP-1_H QVQLVQSGAEVKKPGASVKVSCKASGYIFTDYYMHWVRQAPGQELGWMGRINPNSGGTNY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
:::. : :.. : : :::: ...::: ::::.:::::
DP-1_H AQKFQGRVTMTRDTSISTAYTELSSLRSEDTATYYCAR
190 220 250 280
>>hv1263_3M28-.. (296 aa)
Frame: 1 initn: 434 init1: 434 opt: 434 Z-score: 75.1 expect() 14
64.286% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::.::. : .:: :...:::::: :: :.. :::::::.::::.: : : : .::
hv1263 QVQLVQSGAEVKKPGSSVKVSCKASGGTFSSYAISWVRQAPGQGLEWMGRIIPILGIANY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
:::. : ::..::: ::::....::: ::::::::::
hv1263 AQKFQGRVTITADKSTSTAYMELSSLRSEDTAVYYCAR
190 220 250 280
>>DP-44_HC16-10-.. (293 aa)
Frame: 1 initn: 404 init1: 268 opt: 433 Z-score: 75.1 expect() 14
66.327% identity in 98 aa overlap (1-98:1-291)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
.::::.::::.:.:: :::::: .::: :: :.::::::::::::::.. :. . : : :
DP-44_ EVQLVQSGGGLVHPGGSLRLSCAGSGFTFSSYAMHWVRQAPGKGLEWVSAIG-TGGGTYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :..:.. ::::.::: :: :::::::
DP-44_ ADSVKGRFTISRDNAKNSLYLQMNSLRAEDMAVYYCAR
190 220 250 280
>>8-1B (293 aa)
Frame: 1 initn: 400 init1: 251 opt: 432 Z-score: 75.0 expect() 14
70.408% identity in 98 aa overlap (1-98:1-291)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
.:::::::::.:::: :::::: :::: : : ::::::::::::.. : : : : :
8-1B EVQLVESGGGLVQPGGSLRLSCAASGFTVSSNYMSWVRQAPGKGLEWVSVIY-SGGSTYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: ::::.::: ::::::::::
8-1B ADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>YAC-5 (293 aa)
Frame: 1 initn: 400 init1: 251 opt: 432 Z-score: 75.0 expect() 14
70.408% identity in 98 aa overlap (1-98:1-291)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
.:::::::::.:::: :::::: :::: : : ::::::::::::.. : : : : :
YAC-5 EVQLVESGGGLVQPGGSLRLSCAASGFTVSSNYMSWVRQAPGKGLEWVSVIY-SGGSTYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: ::::.::: ::::::::::
YAC-5 ADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>MTGLa (293 aa)
Frame: 1 initn: 400 init1: 251 opt: 432 Z-score: 75.0 expect() 14
70.408% identity in 98 aa overlap (1-98:1-291)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
.:::::::::.:::: :::::: :::: : : ::::::::::::.. : : : : :
MTGLa EVQLVESGGGLVQPGGSLRLSCAASGFTVSSNYMSWVRQAPGKGLEWVSVIY-SGGSTYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: ::::.::: ::::::::::
MTGLa ADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>12M28 (296 aa)
Frame: 1 initn: 432 init1: 432 opt: 432 Z-score: 74.9 expect() 14
64.286% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::.::. : .:: :...:::::: :: :.. :::::::.::::.: : : : .::
12M28 QVQLVQSGAEVKKPGSSVKVSCKASGGTFSSYAISWVRQAPGQGLEWMGGIIPILGIANY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
:::. : ::..::: ::::....::: ::::::::::
12M28 AQKFQGRVTITADKSTSTAYMELSSLRSEDTAVYYCAR
190 220 250 280
>>V3-53 (293 aa)
Frame: 1 initn: 399 init1: 250 opt: 431 Z-score: 74.9 expect() 14
69.388% identity in 98 aa overlap (1-98:1-291)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
.:::::::::..::: :::::: :::: : : ::::::::::::.. : : : : :
V3-53 EVQLVESGGGLIQPGGSLRLSCAASGFTVSSNYMSWVRQAPGKGLEWVSVIY-SGGSTYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: ::::.::: ::::::::::
V3-53 ADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>RR-VH1.2 (294 aa)
Frame: 1 initn: 431 init1: 431 opt: 431 Z-score: 74.9 expect() 15
64.286% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::.::. : .:: :...:::::: :: :.. :::::::.::::.: : : : .::
RR-VH1 QVQLVQSGAEVKKPGSSVKVSCKASGGTFSSYAISWVRQAPGQGLEWMGGIIPIFGTANY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
:::. : ::.::.: ::::....::: ::::::::::
RR-VH1 AQKFQGRVTITTDESTSTAYMELSSLRSEDTAVYYCAR
190 220 250 280
>>DP-88_hv1051K-.. (296 aa)
Frame: 1 initn: 431 init1: 431 opt: 431 Z-score: 74.8 expect() 15
64.286% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::.::. : .:: :...:::::: :: :.. :::::::.::::.: : : : .::
DP-88_ QVQLVQSGAEVKKPGSSVKVSCKASGGTFSSYAISWVRQAPGQGLEWMGGIIPIFGTANY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
:::. : ::..::: ::::....::: ::::::::::
DP-88_ AQKFQGRVTITADKSTSTAYMELSSLRSEDTAVYYCAR
190 220 250 280
>>DP-29_12-2 (302 aa)
Frame: 1 initn: 404 init1: 263 opt: 431 Z-score: 74.7 expect() 15
68.000% identity in 100 aa overlap (1-98:1-300)
10 20 30 40 50
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYI-NPSRGY-T
.:::::::::.:::: :::::: :::: :: . : ::::::::::::.: : . .: :
DP-29_ EVQLVESGGGLVQPGGSLRLSCAASGFTFSDHYMDWVRQAPGKGLEWVGRTRNKANSYTT
10 40 70 100 130 160
60 70 80 90
OKT3Hh NYNQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.: . : ::::: : ::.. ::::.::. ::::::::::
DP-29_ EYAASVKGRFTISRDDSKNSLYLQMNSLKTEDTAVYYCAR
190 220 250 280
>>1-1 (296 aa)
Frame: 1 initn: 429 init1: 429 opt: 429 Z-score: 74.6 expect() 15
61.224% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::.::. : . : :...::::::. :. : ::::.::::.::::.:.:::. : :::
1-1 QVQLVQSGAEVKKLGASVKVSCKASGYTFTGYYMHWVQQAPGQGLEWMGWINPNSGGTNY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
:::. : :.. : : ::::.... :: .:::::::::
1-1 AQKFQGRVTMTRDTSISTAYMELSRLRSDDTAVYYCAR
190 220 250 280
>>DP-4 (296 aa)
Frame: 1 initn: 421 init1: 421 opt: 429 Z-score: 74.6 expect() 15
60.204% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:.:::.::. : . : :...::::::. :. .::::::::..:::.:.:.: : :::
DP-4 QMQLVQSGAEVKKTGSSVKVSCKASGYTFTYRYLHWVRQAPGQALEWMGWITPFNGNTNY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
:::.:: ::. :.: ::::....::: ::::.:::::
DP-4 AQKFQDRVTITRDRSMSTAYMELSSLRSEDTAMYYCAR
190 220 250 280
>>7-2 (296 aa)
Frame: 1 initn: 421 init1: 421 opt: 429 Z-score: 74.6 expect() 15
60.204% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:.:::.::. : . : :...::::::. :. .::::::::..:::.:.:.: : :::
7-2 QMQLVQSGAEVKKTGSSVKVSCKASGYTFTYRYLHWVRQAPGQALEWMGWITPFNGNTNY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
:::.:: ::. :.: ::::....::: ::::.:::::
7-2 AQKFQDRVTITRDRSMSTAYMELSSLRSEDTAMYYCAR
190 220 250 280
>>DP-42 (293 aa)
Frame: 1 initn: 396 init1: 247 opt: 428 Z-score: 74.6 expect() 15
68.367% identity in 98 aa overlap (1-98:1-291)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
.:::::.:::..::: :::::: :::: : : ::::::::::::.. : : : : :
DP-42 EVQLVETGGGLIQPGGSLRLSCAASGFTVSSNYMSWVRQAPGKGLEWVSVIY-SGGSTYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.. : ::::: :.::.: ::::.::: ::::::::::
DP-42 ADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAR
190 220 250 280
>>HA2 (296 aa)
Frame: 1 initn: 428 init1: 428 opt: 428 Z-score: 74.6 expect() 15
61.224% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
::::: ::. : .:: :...::::::. :. : :.:.:::::.:.::.:.:: . : :.:
HA2 QVQLVXSGAEVKKPGASVKVSCKASGYTFTSYYMNWMRQAPGQGFEWMGWINAGNGNTKY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.::.. : ::. : : ::::.:..::: ::::::::::
HA2 SQKLQGRVTITRDTSASTAYMQLSSLRSEDTAVYYCAR
190 220 250 280
>>6M27 (296 aa)
Frame: 1 initn: 428 init1: 428 opt: 428 Z-score: 74.6 expect() 15
63.265% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::.::. : .:: :...:::::: :: :.. :::::::.::::.: : : : .::
6M27 QVQLVQSGAEVKKPGSSVKVSCKASGGTFSSYAISWVRQAPGQGLEWMGRIIPILGTANY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
:::. : ::..:.: ::::....::: ::::::::::
6M27 AQKFQGRVTITADESTSTAYMELSSLRSEDTAVYYCAR
190 220 250 280
>>LSG4-1 (302 aa)
Frame: 1 initn: 407 init1: 254 opt: 429 Z-score: 74.5 expect() 15
68.367% identity in 98 aa overlap (1-96:1-294)
10 20 30 40 50
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSR--GYT
.:::::::::.:.:: :::::: :::: :: : ::::::::::::.: :. . : :
LSG4-1 EVQLVESGGGLVKPGGSLRLSCAASGFTFSNAWMSWVRQAPGKGLEWVGRIKSKTDGGTT
10 40 70 100 130 160
60 70 80 90
OKT3Hh NYNQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
:: : ::::: : ::.: ::::.::. ::::::::.
LSG4-1 NYAAPVKGRFTISRDDSKNTLYLQMNSLKTEDTAVYYCTT
190 220 250 280
>>YAC-9_COS-27-.. (302 aa)
Frame: 1 initn: 395 init1: 256 opt: 428 Z-score: 74.4 expect() 15
67.000% identity in 100 aa overlap (1-98:1-300)
10 20 30 40 50
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYI--NPSRGYT
.:::::::::.:::: ::.::: :::: :: .::::::: ::::::.: : . . :
YAC-9_ EVQLVESGGGLVQPGGSLKLSCAASGFTFSGSAMHWVRQASGKGLEWVGRIRSKANSYAT
10 40 70 100 130 160
60 70 80 90
OKT3Hh NYNQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
: . : ::::: : ::.::::::.::. ::::::::.:
YAC-9_ AYAASVKGRFTISRDDSKNTAYLQMNSLKTEDTAVYYCTR
190 220 250 280
>>2M27_11M27-.. (296 aa)
Frame: 1 initn: 426 init1: 426 opt: 426 Z-score: 74.4 expect() 16
63.265% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::.::. : .:: :...:::::: :: :.. :::::::.::::.: : : : .::
2M27_1 QVQLVQSGAEVKKPGSSVKVSCKASGGTFSSYAISWVRQAPGQGLEWMGGIIPIFGTANY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
:::. : ::..:.: ::::....::: ::::::::::
2M27_1 AQKFQGRVTITADESTSTAYMELSSLRSEDTAVYYCAR
190 220 250 280
>>VHGL1-8 (296 aa)
Frame: 1 initn: 426 init1: 426 opt: 426 Z-score: 74.4 expect() 16
63.265% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::.::. : .:: :...:::::: :: :.. :::::::.::::.: : : : .::
VHGL1- QVQLVQSGAEVKKPGSSVKVSCKASGGTFSSYAISWVRQAPGQGLEWMGGIIPIFGTANY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
:::. : ::..:.: ::::....::: ::::::::::
VHGL1- AQKFQGRVTITADESTSTAYMELSSLRSEDTAVYYCAR
190 220 250 280
>>DP-10_hv1051-.. (296 aa)
Frame: 1 initn: 426 init1: 426 opt: 426 Z-score: 74.4 expect() 16
63.265% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::.::. : .:: :...:::::: :: :.. :::::::.::::.: : : : .::
DP-10_ QVQLVQSGAEVKKPGSSVKVSCKASGGTFSSYAISWVRQAPGQGLEWMGGIIPIFGTANY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
:::. : ::..:.: ::::....::: ::::::::::
DP-10_ AQKFQGRVTITADESTSTAYMELSSLRSEDTAVYYCAR
190 220 250 280
>>DP-48_13-2 (293 aa)
Frame: 1 initn: 398 init1: 271 opt: 425 Z-score: 74.3 expect() 16
67.347% identity in 98 aa overlap (1-98:1-291)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
.:::::::::.:::: :::::: :::: :: : ::::::: ::::::.. :. . : : :
DP-48_ EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYDMHWVRQATGKGLEWVSAIG-TAGDTYY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
. : ::::: ...:.. ::::.::: :::::::::
DP-48_ PGSVKGRFTISRENAKNSLYLQMNSLRAGDTAVYYCAR
190 220 250 280
>>VHGL1-9 (296 aa)
Frame: 1 initn: 425 init1: 425 opt: 425 Z-score: 74.3 expect() 16
61.224% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::.::. : .:: :...::::::. :. :.:.:::::::. :::.:.: : : .::
VHGL1- QVQLVQSGAEVKKPGASVKVSCKASGYTFTSYAMNWVRQAPGQRLEWMGWIIPIFGTANY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
:::. : ::..:.: ::::....::: :: :::::::
VHGL1- AQKFQGRVTITADESTSTAYMELSSLRSEDMAVYYCAR
190 220 250 280
>>LSG6-1 (302 aa)
Frame: 1 initn: 388 init1: 256 opt: 426 Z-score: 74.2 expect() 16
67.347% identity in 98 aa overlap (1-96:1-294)
10 20 30 40 50
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSR--GYT
.:::::::::.:.:: :::::: :::: :: :.::::::::::::.: :. . : :
LSG6-1 EVQLVESGGGLVKPGGSLRLSCAASGFTFSNAWMNWVRQAPGKGLEWVGRIKSKTDGGTT
10 40 70 100 130 160
60 70 80 90
OKT3Hh NYNQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
.: : ::::: : ::.: ::::.::. ::::::::.
LSG6-1 DYAAPVKGRFTISRDDSKNTLYLQMNSLKTEDTAVYYCTT
190 220 250 280
>>VHVBLK32 (294 aa)
Frame: 1 initn: 421 init1: 421 opt: 423 Z-score: 74.1 expect() 16
62.245% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
.::::.::. : .::.:::.:::.::. :. : . :::: :::::::.: :.:: .::::
VHVBLK EVQLVQSGAEVKKPGESLRISCKGSGYSFTSYWISWVRQMPGKGLEWMGRIDPSDSYTNY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
. .:. . :::.::: :::::: .::. :::.:::::
VHVBLK SPSFQGQVTISADKSISTAYLQWSSLKASDTAMYYCAR
190 220 250 280
>>VI-4-1b (296 aa)
Frame: 1 initn: 423 init1: 423 opt: 423 Z-score: 74.1 expect() 16
61.224% identity in 98 aa overlap (1-98:1-294)
10 20 30 40 50 60
OKT3Hh QVQLVESGGGVVQPGRSLRLSCKASGFIFSRYTMHWVRQAPGKGLEWIGYINPSRGYTNY
:::::.::. . .:: :...::::::. :. :.:.:::::::.::::.:.:: . : .:
VI-4-1 QVQLVQSGSELKKPGASVKVSCKASGYTFTSYAMNWVRQAPGQGLEWMGWINTNTGNPTY
10 40 70 100 130 160
70 80 90
OKT3Hh NQKFKDRFTISTDKSKSTAYLQMDSLRPEDTAVYYCAR
: : ::..: : : ::::::..::. ::::::::::
VI-4-1 AQGFTGRFVFSLDTSVSTAYLQISSLKAEDTAVYYCAR
190 220 250 280
98 residues in 1 query sequences
167154 residues in 638 library sequences
Tcomplib (4 proc)[version 3.2t07 August 17, 1999]
start: Wed Jul 11 18:28:33 2001 done: Wed Jul 11 18:28:34 2001
Scan time: 0.280 Display time: 0.150
Function used was TFASTA
Date: Thu, 12 Jul 2001 19:07:56 +0100
TFASTA translates and searches a DNA sequence data bank
version 3.2t07 August 17, 1999
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
/tmp/.fasta3-search-2131554: 21 aa
>OKT3HhJ
vs V-Base Nucleic library
searching /data/V-Base/D_VBASE.txt library
searching /data/V-Base/JH_VBASE.txt library
searching /data/V-Base/JK_VBASE.txt library
searching /data/V-Base/JL_VBASE.txt library
searching /data/V-Base/VH_VBASE.txt library
searching /data/V-Base/VK_VBASE.txt library
searching /data/V-Base/VL_VBASE.txt library
167154 residues in 638 sequences
Expectation_n fit: rho(ln(x))= 2.2935+/-0.00828; mu= 11.5101+/- 0.467;
mean_var=15.4459+/-10.543, 0's: 3 Z-trim: 12 B-trim: 0 in 0/18
TFASTA (3.27 August, 1999) function [optimized, BL50 matrix (15:-5)] ktup: 2
join: 36, opt: 36, gap-pen: -16/ -2, width: 16 reg.-scaled
Scan time: 0.150
The best scores are: initn init1 opt z-sc E(623)
JH6a ( 63) [3] 67 67 86 215.4 2.2e-07
JH6b ( 63) [3] 67 67 86 215.4 2.2e-07
JH4b ( 48) [3] 80 80 81 204.2 9e-07
JH4d ( 48) [3] 80 80 81 204.2 9e-07
JH4a ( 48) [3] 80 80 81 204.2 9e-07
JH6c ( 63) [3] 62 62 81 202.6 1.1e-06
JH3b ( 50) [2] 65 65 73 183.6 1.3e-05
JH3a ( 50) [2] 65 65 73 183.6 1.3e-05
JH5a ( 51) [3] 64 64 71 178.4 2.5e-05
JH5b ( 51) [3] 64 64 70 175.9 3.4e-05
JH1 ( 52) [1] 64 64 67 168.1 9.2e-05
JH2 ( 53) [2] 58 58 67 168.0 9.3e-05
FL6_TL6 ( 296) [1] 39 39 59 137.6 0.0046
JHpsi2 ( 54) [2] 46 46 46 114.5 0.09
JHpsi2 ( 54) [3] 45 45 46 114.5 0.09
JL1 ( 38) [1] 43 43 43 108.9 0.18
7a-2.3_DPL18... ( 294) [3] 45 45 46 104.6 0.32
V2-10P ( 285) [2] 44 44 45 102.2 0.43
V201 ( 296) [1] 41 41 44 99.5 0.61
IGGLL295 ( 264) [1] 39 39 39 87.4 2.9
>>JH6a (63 aa)
Frame: 3 initn: 67 init1: 67 opt: 86 Z-score: 215.4 expect() 2.2e-07
65.000% identity in 20 aa overlap (2-21:3-62)
10 20
OKT3Hh YYDDHYCLDYWGQGTPVTVSS
: .: .: ::::: :::::
JH6a YYYYYGMDVWGQGTTVTVSS
30 60
>>JH6b (63 aa)
Frame: 3 initn: 67 init1: 67 opt: 86 Z-score: 215.4 expect() 2.2e-07
65.000% identity in 20 aa overlap (2-21:3-62)
10 20
OKT3Hh YYDDHYCLDYWGQGTPVTVSS
: .: .: ::::: :::::
JH6b YYYYYGMDVWGQGTTVTVSS
30 60
>>JH4b (48 aa)
Frame: 3 initn: 80 init1: 80 opt: 81 Z-score: 204.2 expect() 9e-07
85.714% identity in 14 aa overlap (8-21:6-47)
10 20
OKT3Hh YYDDHYCLDYWGQGTPVTVSS
.::::::: :::::
JH4b YFDYWGQGTLVTVSS
30
>>JH4d (48 aa)
Frame: 3 initn: 80 init1: 80 opt: 81 Z-score: 204.2 expect() 9e-07
85.714% identity in 14 aa overlap (8-21:6-47)
10 20
OKT3Hh YYDDHYCLDYWGQGTPVTVSS
.::::::: :::::
JH4d YFDYWGQGTLVTVSS
30
>>JH4a (48 aa)
Frame: 3 initn: 80 init1: 80 opt: 81 Z-score: 204.2 expect() 9e-07
85.714% identity in 14 aa overlap (8-21:6-47)
10 20
OKT3Hh YYDDHYCLDYWGQGTPVTVSS
.::::::: :::::
JH4a YFDYWGQGTLVTVSS
30
>>JH6c (63 aa)
Frame: 3 initn: 62 init1: 62 opt: 81 Z-score: 202.6 expect() 1.1e-06
60.000% identity in 20 aa overlap (2-21:3-62)
10 20
OKT3Hh YYDDHYCLDYWGQGTPVTVSS
: .: .: ::.:: :::::
JH6c YYYYYYMDVWGKGTTVTVSS
30 60
>>JH3b (50 aa)
Frame: 2 initn: 65 init1: 65 opt: 73 Z-score: 183.6 expect() 1.3e-05
78.571% identity in 14 aa overlap (8-21:8-49)
10 20
OKT3Hh YYDDHYCLDYWGQGTPVTVSS
.: ::::: :::::
JH3b DAFDIWGQGTMVTVSS
20
>>JH3a (50 aa)
Frame: 2 initn: 65 init1: 65 opt: 73 Z-score: 183.6 expect() 1.3e-05
78.571% identity in 14 aa overlap (8-21:8-49)
10 20
OKT3Hh YYDDHYCLDYWGQGTPVTVSS
.: ::::: :::::
JH3a DAFDVWGQGTMVTVSS
20
>>JH5a (51 aa)
Frame: 3 initn: 64 init1: 64 opt: 71 Z-score: 178.4 expect() 2.5e-05
78.571% identity in 14 aa overlap (8-21:9-50)
10 20
OKT3Hh YYDDHYCLDYWGQGTPVTVSS
.: ::::: :::::
JH5a NWFDSWGQGTLVTVSS
30
>>JH5b (51 aa)
Frame: 3 initn: 64 init1: 64 opt: 70 Z-score: 175.9 expect() 3.4e-05
78.571% identity in 14 aa overlap (8-21:9-50)
10 20
OKT3Hh YYDDHYCLDYWGQGTPVTVSS
.: ::::: :::::
JH5b NWFDPWGQGTLVTVSS
30
>>JH1 (52 aa)
Frame: 1 initn: 64 init1: 64 opt: 67 Z-score: 168.1 expect() 9.2e-05
71.429% identity in 14 aa overlap (8-21:10-51)
10 20
OKT3Hh YYDDHYCLDYWGQGTPVTVSS
...::::: :::::
JH1 AEYFQHWGQGTLVTVSS
10 40
>>JH2 (53 aa)
Frame: 2 initn: 58 init1: 58 opt: 67 Z-score: 168.0 expect() 9.3e-05
58.824% identity in 17 aa overlap (5-21:2-52)
10 20
OKT3Hh YYDDHYCLDYWGQGTPVTVSS
.. .: ::.:: :::::
JH2 YWYFDLWGRGTLVTVSS
20 50
>>FL6_TL6 (296 aa)
Frame: 1 initn: 39 init1: 39 opt: 59 Z-score: 137.6 expect() 0.0046
63.636% identity in 11 aa overlap (4-14:259-291)
10 20
OKT3Hh YYDDHYCLDYWGQGTPVTVSS
::::. : :.:.
FL6_TL PSGVPGRFSGSILGNKAALTITGTQVDDDSDHYCVLYMGSGN
190 220 250 280
>>JHpsi2 (54 aa)
Frame: 2 initn: 46 init1: 46 opt: 46 Z-score: 114.5 expect() 0.09
77.778% identity in 9 aa overlap (12-20:23-49)
10 20
OKT3Hh YYDDHYCLDYWGQGTPVTVSS
:::.: :::
JHpsi2 LQVLGALGQGSPDTVSL
20 50
>>JHpsi2 (54 aa)
Frame: 3 initn: 45 init1: 45 opt: 46 Z-score: 114.5 expect() 0.09
57.143% identity in 7 aa overlap (7-13:9-29)
10 20
OKT3Hh YYDDHYCLDYWGQGTPVTVSS
::..::..
JHpsi2 YKCLEHWGRAARTPSPW
30
21 residues in 1 query sequences
167154 residues in 638 library sequences
Tcomplib (4 proc)[version 3.2t07 August 17, 1999]
start: Thu Jul 12 19:07:56 2001 done: Thu Jul 12 19:07:56 2001
Scan time: 0.150 Display time: 0.020
Function used was TFASTA
To be added
To be added
Mike Clark