Publications
- Watson CJ, Khaled WT. (2008) Mammary development in the embryo and adult: a journey of morphogenesis and commitment. Development 135(6):995-1003.
- Khaled WT, Read EK, Nicholson SE, Baxter FO, Brennan AJ, Came PJ, Sprigg N, McKenzie AN, Watson CJ. (2007) The IL-4/IL-13/Stat6 signalling pathway promotes luminal mammary epithelial cell development. Development 134(15):2739-50.
- Baxter, F.O., Came, P.J., Abell, K., Kedjouar, B., Huth, M., Rajewsky, K., Pasparakis, M., Watson C.J. (2006) IKKb/2 induces TWEAK and apoptosis in mammary epithelial cells. Development 133(17):3485-3494.
- Robson EJ, Khaled WT, Abell K, Watson CJ (2006) Epithelial-to-mesenchymal transition confers resistance to apoptosis in three murine mammary epithelial cell lines. Differentiation 74(5):254-64
- Watson, CJ (2006) Post-lactational mammary gland regression: molecular basis and implications for breast cancer. Expert Rev Mol Med. 8(32):1-15.
- Clarkson RW, Boland MP, Kritikou EA, Lee JM, Freeman TC, Tiffen PG, Watson, CJ (2006) The genes induced by signal transducer and activators of transcription (STAT)3 and STAT5 in mammary epithelial cells define the roles of these STATs in mammary development. Mol Endocrinol. 20(3):675-685.
- Abell, K., Bilancio, A., Clarkson, R.W., Tiffen, P.G., Altaparmakov,
A.I., Burdon, T.G., Asano, T., Vanhaesebroeck, B., Watson, C. J. (2005) Stat3-induced
apoptosis requires a molecular switch in PI(3)K subunit composition. Nat Cell
Biol. 7, 392-398. Pubmed
- Clarkson, R.W.E., Wayland, M.T., Lee, J ., Freeman, T., and Watson,
C.J. (2004) Gene expression profiling of mammary gland development reveals
putative roles for death receptors and immunity in post-lactational regression.
Breast Cancer Res. 6,R92-R109. Pubmed
- Kritikou, E.A., Sharkey, A., Abell, K., Came, P.J., Anderson, E.,
Clarkson R. W. E. and Watson, C.J. (2003) Leukaemia inhibitory factor signals
alternately through ERK and Stat3 to regulate mammary gland development. Development
130,3459-3468. Pubmed
- Clarkson, R.W.E. and Watson, C.J. (2003) Microarray analysis of the
involution switch. J Mammary Gland Biol Neoplasia, 8, 309-319. Pubmed
- Gordon,K.E., Binas,B., Chapman,R.S., Kurian,K.M., Clarkson,R.W.E.,
Clark,A.J., Lane,E.B., and Watson,C.J. (2000) A novel cell culture model for
studying differentiation and apoptosis in the mouse mammary gland Breast Cancer
Res. 2 222-235. Pubmed
- Chapman RS, Lourenco PC, Tonner E, Flint DJ, Selbert S, Takeda K,
Akira S, Clarke AR, Watson CJ, (1999) Suppression of epithelial apoptosis
and delayed mammary gland involution in mice with a conditional knockout of
Stat3, Genes & Development 13(19): 2604-16. Pubmed
- Richardson M, Redmond D, Watson CJ and Mason JO, (1999) Mouse Wnt8B
is expressed in the developing forebrain and maps to chromosome 19, Mammalian
Genomics 10(9): 923-5. Pubmed
- Clarkson RW and Watson CJ, (1999) NF-kappaB and apoptosis in mammary
epithelial cells, Journal of Mammary Gland Biology and Neoplasia 4(2): 165-75.
Pubmed
- Kurian KM, Watson CJ and Wyllie AH, (1999) DNA chip technology, Journal
of Pathology 187(3): 267-71. Pubmed
- Rich T, Watson CJ and Wyllie AH, (1999) Apoptosis: the germs of death,
Nature Cell Biology 1(3): E69-E71. Pubmed
- Selbert S, Bentley DJ, Melton DW, Rannie D, Lourenco P, Watson CJ
and Clark AR (1998) Efficient BLG-Cre mediated gene deletion in the mammary
gland, Transgenic Research 7(5): 387-96. Pubmed
- Miller WR, Mullen P, Sourdaine P, Watson CJ, Dixon JM and Telford
J, (1997) Regulation of aromatase activity within the breast, Journal of Steroid
Biochemistry and Molecular Biology 61(3-6): 193-202. Pubmed
- Watson CJ, Burdon TG, (1996) Prolactin signal transduction mechanisms
in the mammary gland: the role of the Jak/Stat pathway, Reproduction 1(1):
1-5. Pubmed
- MacLaren AP, McBride D, Watson CJ, Clinton M, (1996) Identification
of transcripts showing differential expression in the developing mammary gland
using differential display, Biochemical Society Transactions 24(3): 273S.
Pubmed
- Philp JA, Burdon TG, Watson CJ, (1996) Differential regulation of
members of the family of signal transducers and activators of transcription
during mammary gland development, Biochemical Society Transactions 24(3):
370S. Pubmed
- Philp JA, Burdon TG, Watson CJ, (1996) Differential activation of
STATs 3 and 5 during mammary gland development, FEBS Letters 396(1): 77-80.
Pubmed
- Streuli CH, Edwards GM, Delcommenne M, Whitelaw CB, Burdon TG, Schindler
C, Watson CJ, (1995) Stat5 as a target for regulation by extracellular matrix,
Journal of Biological Chemistry 270(37): 21639-44. Pubmed
- Watson CJ, Miller WR, (1995) Elevated levels of members of the STAT
family of transcription factors in breast carcinoma nuclear extracts, British
Journal of Cancer 71(4): 840-4. Pubmed
- Demmer J, Burdon TG, Djiane J, Watson CJ, Clark AJ, (1995) The proximal
milk protein binding factor binding site is required for the prolactin responsiveness
of the sheep beta-lactoglobulin promoter in Chinese hamster ovary cells, Molecular
and Cellular Endocrinology 107(1): 113-21. Pubmed
- Burdon TG, Maitland KA, Clark AJ, Wallace R, Watson CJ, (1994) Regulation
of the sheep beta-lactoglobulin gene by lactogenic hormones is mediated by
a transcription factor that binds an interferon-gamma activation site-related
element, Molecular Endocrinology 8(11): 1528-36. Pubmed
- Watson CJ, Gordon KE, Robertson M, Clark AJ, (1991) Interaction of
DNA-binding proteins with a milk protein gene promoter in vitro: identification
of a mammary gland-specific factor, Nucleic Acids Research 19(23): 6603-10.
Pubmed
