Research
Virology

Viruses continue to pose a serious threat to human health and considerable worldwide efforts are being focused on understanding the molecular biology of viruses and the mechanisms by which they cause disease. Staff and students in the Division of Virology pursue a wide range of research interests. The topics of research on RNA viruses include the replication mechanisms of influenza A virus, the molecular biology of positive strand RNA viruses (caliciviruses, picornavirus) and translational control of virus gene expression (coronaviruses and retroviruses). Research on DNA viruses is largely focused on gammaherpesvirus pathogenesis and immune evasion, herpes simplex virus latency, herpesvirus entry, assembly and egress and the pathogenesis of human papillomavirus infections. There are also extensive collaborations with virologists in the Department of Medicine and the Cambridge Veterinary School. A more detailed description of the Division can be found here: www.virology.path.cam.ac.uk
Research projects within this thematic include;
- Norovirus pathogenesis and virus-Host interactions (Professor Ian Goodfellow)
- Messenger RNA structure & translational control of virus gene expression (Dr Ian Brierley)
- Molecular studies of positive strand RNA viruses (Dr David Brown)
- Entry and Assembly of Herpesviruses (Dr Helena Browne)
- The Cell Biology of Herpesvirus Assembly and Egress. (Dr Colin Crump)
- Herpesvirus Pathogenesis (Dr Stacey Efstathiou)
- Immune and genetic analyses in HPV disease (Dr Peter Goon)
- Transcription Regulation and Cancer (Professor Tony Kouzarides)
- Pathogenesis of Human Papillomavirus Infections (Professor Margaret Stanley & Dr Jane Sterling)
- Anti-viral Immunity and Viral Immune Evasion (Dr Philip Stevenson)
