Publications 2012
- Affara NA, Quilter CR, Sargent CA Bauer J, Bagga MR, Reiter CP, Hutchinson EL, Southwood OI, Evans G, Mileham A, Griffin DK (2012)
An association and haplotype analysis of porcine maternal infanticide: a model for human puerperal psychosis?
American Journal of Medical Genetics B: Neuropsychiatric Genetics 159(8): 908-927 - Affara NA, Wang SJ, Liu WJ, Yang LG, Liu HB, Sargent CA, Zhang SJ (2012)
Association of multi-pathogenic infections with BAT2, CXCL12, Mx1 and EHMT2 variations in pigs.
Molecular Biology Reports 39: 8169-8176 - Affara NA, Cooper WN, Khulan B, Owens S, Elks CE, Seidel V, Prentice AM, Belteki G, Ong KK, Constancia M, Dunger DB (2012)
DNA methylation profiling at imprinted loci after periconceptional micronutrient supplementation in humans: results of a pilot randomized controlled trial.
The FASEB Journal 26(5): 1782-1790 - Affara NA, Cocquet J, Ellis PJI, Mahadevaiah SK, Vaiman D, Burgoyne PS (2012)
A genetic basis for a postmeiotic X versus Y chromosome intragenomic conflict in the mouse.
PLoS Genetics 8(9): e1002900 - Affara NA, Khulan B, Cooper WN, Skinner BM, Bauer J, Owens S, Prentice Am, Belteki G, Constancia M, Dunger D (2012)
Periconceptional maternal micronutrient supplementation is associated with widespread gender related changes in epigenome: a study of a unique resource in the Gambia.
Human Molecular Genetics 21(9): 2086-2101 - Affara NA, Ren YW, Zhang YY, Sargent CA, Yang LG, Zhao JL, Fang LR, Wu JJ, Fang R, Tong Q, Xiao J, Li JL, Jiang YB, Chen HC, Zhang SJ (2012)
The polymorphism analysis of CD169 and CD 163 related with the risk of porcine reproduction and respiratory syndrome virus (PRRSV) infection.
Molecular Biology Reports 39(11): 9903-9909 - Ajioka JW, Su C, Khan A, Zhou P, Majumdar D, Ajzenberg D, Darde M-L, Zhu X-Q, Rosenthal BM, Dubey JP, Sibley LD (2012)
Globally diverse Toxoplasma gondii isolates comprise six major clades originating from a small number of distinct ancestral lineages.
Proceedings of the National Academy of Sciences of the United States of America 109(15): 5844-5849 - Arends NA, Gay LJ, Mitrou PN, Keen J, Bowman R, Naguib A, Cooke J, Kuhnle G, Burns PA, Luben R, Lentjes M, Khaw K-T, Ball RY, Ibrahim EK (2012)
Dietary, lifestyle and clinicopathological factors associated with APC mutations and promoter methylation colorectal cancers from the EPIC-Norfolk study.
Journal of Pathology 228: 405-415 - Arends NA, McIntyre RE, Chavali PL, Ismail O, Carragher DM, Sanchez-Andrade G, Forment JV, Fu B and others
Disruption of mouse cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndrome.
PLoS Genetics 8(11): e1003022 - Arends NA, Migdalska AM, Weyden L van der, Ismail O, Rust AG, Rashid M, White JK, Sanchez-Andrade G, Lupski JR, Logan DW, Adam DJ (2012)
Generation of the Sotos syndrome deletion in mice.
Mammalian Genome 23: 749-757 - Arends NA, Garaycoechea JI, Crossan GP, Langevin F, Daly M, Patel KJ (2012)
Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function.
Nature 489: 571-575 - Arends NA, Weyden L van der, Papaspyropoulos A, Poulogiannis G, Rust AG, Rashid M, Adams DJ, O’Neil E (2012)
Loss of Rassf1a synergizes with deregulated runx2 signaling in tumourigenesis.
Cancer Research 72(15): 3817-3827 - Arends NA, Wilson CH, Crombie C, Weyden L van der, Poulogiannis G, Rust AG, Pardo M, Gracia T, Yu L, Choudhary J, Poulin GB, McIntyre RE, Winton DJ, March HN, Fraser AG, Adams DJ (2012)
Nuclear receptor binding protein 1 regulates intestinal progenitor cell homeostasis and tumour formation.
The Embo Journal 31: 2486-2497 - Brierley I, Nikolic EIC, King LM, Vidaakovic M, Irigoyen N (2012)
Modulation of ribosomal frameshifting frequency and its effect on the replication of Rous Sarcoma Virus.
Journal of Virology 86(21): 11581-11594 - Brierley I, Firth AE (2012)
Non-canonical translation in RNA viruses.
Journal of General Virology 93: 1385-1409 - Brierley I, Lin Z, Gilbert JC (2012)
Spacer-length dependence of programmed -1 or -2 ribosomal frameshifting on a U6A heptamer supports a role for messenger RNA (mRNA) tension in frameshifting.
Nucleic Acids Research 40(17): 8674-8689 - Clark MR, Armour KL (2012)
Binding molecules with biased recognition.
Patent Number: WO/2012/146934, 1st November 2012 - Clark MR, Armour KL (2012)
Polypeptides including modified constant regions.
Patent Number: US20120039907 A1(USA), 16th February 2012 - Coleman N, Saeb-Parsy K, Wilson A, Scarpini C, Corcoran M, Chilcott S, McKean M, Thottakam B, Rai B, Nabi G, Rana D, Perera M, Stewart K, Laskey RA, Neal DE (2012)
Diagnosis of bladder cancer by immunocytochemical detection of minichromosome maintenance protein-2 in cells retrieved from urine.
British Journal of Cancer 107: 1384-1391 - Coleman N, Carter SA, Foster NA, Scarpini CG, Chattopadhyay A, Pett MR, Roberts I (2012)
Lipoprotein lipase is frequently overexpressed or translocated in cervical squamous cell carcinoma and promotes invasiveness through the non-catalytic C terminus.
British Journal of Cancer 107: 739-747 - Coleman N, Wechsler EI, Wang Q, Roberts I, Pagliarulo E. Jackson D, Untersperger C, Griffin H, Doorbar J (2012)
Reconstruction of human papillomavirus type 16-mediated early-stage neoplasia implicates E6/E7 deregulation and the loss of contact inhibition in neoplastic progression.
Journal of Virology 86(11): 6358-6364 - Coleman N, Verma S, Tachtatzis P, Penrhyn-Lowe S, Scarpini C, Jurk D, Zglinicki T von, Alexander GJM (2012)
Sustained telomere length in hepatocytes and cholangiocytes with increasing age in normal liver.
Hepatology 56(4): 1510-1520 - Coleman N, Aravinthan A, Verma S, Davies S, Allison M, Alexander G (2012)
Vacuolation in hepatocyte nuclei is a marker of senescence.
Journal of Clinical Pathology 65(6): 557-560 - Coleman N, Murray MJ (2012)
Testicular Cancer: A new generation of biomarkers for malignant germ cell tumours.
Nature Reviews Urology 9(6): 298-300 - Collins VP, Gessi M, Lambert SR, Lauriola L, Waha A, Pietsch T (2012)
Absence of KIAA1549-BRAF fusion in rosette-forming glioneuronal tumors of the fourth ventricle (RGNT).
Journal of Neuropathologica 110(1): 21-25 - Collins VP, Kool M, Jones DTW, Jaeger N, Northcott PA, Hovestadt V, Remke M, Schueller U, and others (2012)
Adult SHH-medulloblastomas show a distinct mutation spectrum, transcriptome and methylome.
Pedriatric Blood and Cancer 59(6): 980-981 - Collins VP, Ida CM, Lambert SR, Rodriguez FJ, Voss JS, Brooke E, McCann BE, Seys AR, Halling KC, Giannini C (2012)
BRAF alterations are frequent in cerebellar low-grade astrocytomas with diffuse growth pattern.
Journal of Neuropathology and Experimental Neurology 71(7): 631-639 - Collins VP, Korshunov A, Remke M, Kool M, Hielscher T, Northcott PA, Williamson D, Pfaff E, Witt H, Jones DTW, Ryzhova M, Cho Y-J, Wittmann A, Benner A, Weiss WA, Deimling A von, Scheurlen W, Kulozik AE, Clifford SC, Westermann F, Taylor MD, Lichter P, Pfister SM (2012)
Biological and clinical heterogeneity of MYCN-amplified medulloblastoma.
Acta Neuropathologica 123(4): 515-527 - Collins VP and others (2012)
Clonal selection drives genetic divergence of metastic medulloblastoma.
Nature 482 (7386): 529-533 - Collins VP and others (2012)
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma.
Nature 482 (7384): 226-231 - Collins VP, Piccirillo SGM, Dietz S, Madhu B, Griffiths J, Price SJ, Watts C (2012)
Fluorescence-guided surgical sampling of glioblastoma identifies phenotypically distinct tumour-initiating cell populations in the tumour mass and margin.
British Journal of Cancer 107: 462-468 - Collins VP and others (2012)
Hotspot mutations define distinct epigenetic and biological subgroups of pediatric and young adult glioblastoma.
Pediatric Blood and Cancer 59(6): 1003-1003 - Collins VP and others (2012)
Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations and clinical data of WNT, SHH, group 3 and group 4 medulloblastomas.
Acta Neuropathologica 123(4): 473-484 - Cooke A, Bending D, Zaccone P (2012)
Inflammation and type one diabetes.
International Immunology 24(6): 339-346 - Cooke A (2012)
Parasitic worms and inflammatory disease.
Current Opinion in Rheumatology 24(4): 394-400 - D’Avino PP, Capalbo L, Montembault E, Takeda T, Bassi ZI, Glover DM (2012)
The chromosomal passenger complex controls the function of endosomal sorting complex required for transport-III Snf7 proteins during cytokinesis.
Open Biology 2(5): 120070 - Du M-Q, Liu H, Yan Q, Nuako-Bandoh B, Grigoropoulos N, Huang Y, Follows G, Grant J, Lawton H, Wright P (2012)
Richter’s transformation: clonal identity does not indicate a linear disease progression.
British Journal of Haematology 157(1):136-9 - Du M-Q, Yan Q, Huang Y, Watkins AJ, Kocialkowski S, Hamoudi RA, Isaacson PG, de Leval L, Wotherspoon A (2012)
BCR and TLR signalling pathways are recurrently targeted by genetic changes in splenic marginal zone lymphomas.
Haematologica 97(4): 595-8 - Du M-Q, Hirsch B, Grünbaum M, Wagner F, Bi Y, Lucka L, Stein H, Dürkop H (2012)
A novel a20 (tnfaip3) antibody (ber-a20) detects the unmutated A20 by immunohistology.
Histopathology 60(6B): E19-27 - Du M-Q, Bi Y, Zeng N, Chanudet E, Huang Y, Hamoudi RA, Liu H, Dong G, Watkins AJ, Ley SC, Zou L, Chen R, Zhu X (2012)
A20 inactivation in ocular adnexal MALT lymphoma.
Haematologica 97(6):926-30 - Du M-Q, Connick P, Kolappan M, Crawley C, Webber DJ, Patani R, Michell AW, Luan S-L, Altmann DR, Thompson AJ, Compston A, Scott MA, Miller DH, Chandran S (2012)
Autologous mesenchymal stem cells for the treatment of secondary progressive multiple sclerosis: an open-label phase 2a proof-of-concept study.
Lancet Neurology 11(2): 150-156 - Du M-Q, Wright TM, Rule S, Liu H, Smith ME. (2012)
Extranodal marginal zone lymphoma of the uterine corpus.
Leuk Lymphoma. 53(9):1831-4. Epub 2012 Mar 13. - Du M-Q, Rothberg, PG, Langerak AW, Verhaaf B, van Dongen JJM, Burack WR, Johnson MD, Slate D, Laughlin TS, Payne K, Figueiredo L, Bandoh BN, Yan Q, Bacon CM, Wright P, Bench A, Liu L. (2012)
Clonal antigen receptor gene PCR products outside the expected size range.
Journal of Hematopathology. 5:57-67 - Du M-Q, Vicente-Dueñas C, Fontán L, Gonzalez-Herrero I, Romero-Camarero I, Segura V, Aznar MA, Alonso-Escudero E, Campos-Sanchez E, Ruiz-Roca L, Barajas-Diego M, Sagardoy A, Martinez-Ferrandis JI, Abollo-Jimenez F, Bertolo C, Peñuelas I, Garcia-Criado FJ, García-Cenador MB, Tousseyn T, Agirre X, Prosper F, Garcia-Bragado F, McPhail ED, Lossos IS, Flores T, Hernandez-Rivas JM, Gonzalez M, Salar A, Bellosillo B, Conde E, Siebert R, Sagaert X, Cobaleda C, Sanchez-Garcia I, Martinez-Climent JA. (2012)
Expression of MALT1 oncogene in hematopoietic stem/progenitor cells recapitulates the pathogenesis of human lymphoma in mice.
Proc Natl Acad Sci U S A. 109(26):10534-9 - Du M-Q, Dong G, Huang Y, Yan Q, Chanudet E, Ye H, Liu H, Isaacson PG, Rodriguez-Justo M. (2012)
A rare case of gastric MALT lymphoma resistant to multiple treatment regimens.
J Clin Pathol. ;65:1049-50 - Du M-Q, Watkins AJ, Hamoudi RA, Zeng N, Yan Q, Huang Y, Liu H, Zhang J, Braggio E, Fonseca R, de Leval L, Isaacson PG, Wotherspoon A, McPhail ED, Dogan A. (2012)
An Integrated genomic and expression analysis of 7q deletion in SMZL.
PLoS ONE 7(9): e44997. doi:10.1371 - Du M-Q, Carbone A, Santoro A, Gloghini A (2012)
B-cell lymphomas: From early lesions of uncertain significance to aggressive lymphomas.
Journal of Clinical Pathology 65: 955-8 - Dunne DW, Wilson S (2012)
Advances in our understanding of the epidemiology of Plasmodium and schistosome infection: informing coinfection studies.
Current Opinion in HIV and AIDS 7(3): 225-230 - Dunne DW, Gong YY, Wilson S, Mwatha JK, Routledge MN, Castelino JM, and others (2012)
Aflatoxin exposure may contribute to chronic hepatomegaly in Kenyan school children.
Environmental Health Perspectives 120 (6): 893-896 - Dunne DW, Diepen A van, Smit CH, Egmond L van, Kabatereine NB, Pinot de Moira A, Hokke CH (2012)
Differential anti-glycan antibody responses in Schistosoma mansoni-infected children and adults studies by shotgun glycan microarray.
PLoS Neglected Tropical Diseases 6(11): e1922 - Dunne DW, Mazigo HD, Nuwaha F, Kinung’hi SM, Morona D, Pinot de Moira A, Wilson S, Heukelbach J (2012)
Epidemiology and control of human schistosmiasis in Tanzania.
Parasites and Vectors 5: 274 - Dunne DW, Fitzsimons CM, Jones FM, Pinot de Moira A, Protasio AV, Khalife J, Dickinson HA, Tukahebwa EM (2012)
Progessive cross-reactivity in IgE responses: an explanation for the slow development of human immunity to Schistosomiasis?
Infection and Immunity 80(12): 4264-4270 - Dunne DW, Fitzsimmons CM, Jones FM, Steam A, Chalmers IW, Hoffmann KF, Wawrzyniak J, Wilson S, Kabatereine NB (2012)
The Schistosoma mansoni tegumental-allergen-like (TAL) protein family: Influence of developmental expression on human IgE responses.
PLoS Neglected Tropical Diseases 6(4): e1593 - Dunne DW, Protasio AV, Tsai IJ, Babbage A, Nichol S and others (2012)
A systematically improved high quality genome and tanscriptome of the human blood fluke Schistosoma mansoni.
PLoS Neglected Tropical Diseases 6(1): e 1455 - Edwards PAW, Howarth KD (2012)
Are breast cancers driven by fusion genes?
Breast Cancer Research 14(2): 303-304 - Edwards PAW, Chandra T, Kirschner K, Thuret J-Y and others (2012)
Independence of repressive histone marks and chromatin compaction during senescent heterochromatic layer formation.
Molecular Cell 47(2): 203-214 - Efstathiou S, Nicoll MP, Proenca JT, Connor V (2012)
Influence of herpes simplex virus 1 latency-associated transcripts on the establishment and maintenance of latency in the ROSA26R reporter mouse model.
Journal of Virology 86(16): 8848-8858 - Efstathiou S, Wash R, Calabressi S, Franz S, Griffiths SJ, Wise H, Digard P and others (2012)
Permissive and restricted virus infection of murine embryonic stem cells.
Journal of General Virology 93: 2118-2130 - Field MC, Jackson AP, Berry A, Aslett M, Allison HC, Burton P and others (2012)
Antigenic diversity is generated by distinct evolutionary mechanisms in African trypanosome species.
Proceedings of the National Academy of Sciences of the United States of America 109(9); 3416-3421 - Field MC, Alsford S, DuBois K, Horn D (2012)
Epigenetic mechanisms, nuclear architecture and the control of gene expression in trypanosomes.
Expert Reviews in Molecular Medicine 14, Article number: 213 - Field MC, Alsford S, Eckert S, Baker N, Glover L, Sanchez-Flores A, Leung KF, Turner DJ, Berriman M, Horn D (2012)
High-throughput decoding of antitrypanosomal drug efficacy and resistance,
Nature 482 (7384): 232-236 - Field MC, DuBois KN, Alsford S, Holden JM, Buisson J, Swiderski M, Bart M, Ratushny AV, Wan Y, Bastin P, Barry JD, Navarro M, Horn D, Aitchison JD, Rout MP (2012)
NUP-1 is a large coiled-coil nucleoskeletal protein in trypanosomes with lamin-like functions.
PLoS Biology 10(3): e1001287 - Field MC, Adung’a V, Obado S, Chait BT, Rout MP (2012)
Proteomics on the rims: insights into the biology of the nuclear envelope and flagellar pocket of trypanosomes.
Parasitology 139: 1158-1167 - Field MC, Lo JCY, Jamsai D, O’Conner AE, Borg C and others (2012)
RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport and tail assembly.
PLOS Genetics 8(10): 31002969 - Field MC, Elias M, Brighouse A, Gabernet-Castello C, Dacks JB (2012)
Sculpting the endomembrane system in deep time: high resolution phylogenetics of Rab GTPases.
Journal of Cell Science 125(10): 2500-2508 - Field MC, Horn D, Alsford S, Koreny L, Rout MP (2012)
Telomeres, tethers and trypanosomes.
Nucleus 3(6): 478-486 - Field MC, Ramasamy R (2012)
Terminal galactosylation of glycoconjugates in Plasmodium falciparum asexual blood stages and Trypanosoma brucei bloodstream trypomastigotes.
Experimental Parasitology 130: 314-320 - Firth AE, Ren Q, Wang QS, Chan MMY, Gouw JW, Guarna MM, Foster LJ, Atkins JF, Jan E (2012)
Alternative reading frame selection mediated by a tRNA-like domain of an internal ribosome entry site.
Proceedings of the National Academy of Sciences of the United States of America 109(11): E630-E639 - Firth AE, Jagger BW, Wise HM, Kash JC, Walters KA, Will NM, Xiao Y-L, Dunfee RL, Schwartzman LM, Ozinsky A, Bell GL, Dalton RM, Lo A, Efstathiou S, Atkins JF, Taubenberger JK (2012)
An overlapping protein-coding region in influenza A virus segment 3 modulates the host response.
Science 337: 199-204 - Firth AE, Fang Y, Treffers EE, Li Y, Tas A, Sun Z, Meer Y van der, Ru AH de, Veelen PA van de, Atkins JF, Snijder EJ (2012)
Efficient -2 frameshifting by mammalian ribosomes to synthesize an additional arterivirus protein.
Proceedings of the National Academy of Sciences of the United States of America 109(43): E2920-E2928 - Firth AE, Wise HM, Hutchinson EC, Jagger BW, Stuart AD, Kang ZH, Robb N, Schwartzman LM, Kash JC, Fodor E, Gog JR, Taubenberger JK, Digard P (2012)
Identification of a novel splice variant form of the influenza A virus M2 ion channel with an antigenically distinct ectodomain.
PLoS Pathogens 8(11): e1002998 - Firth AE, Brierley I (2012)
Non-canonical translation in RNA viruses.
Journal of General Virology 93: 1385-1409 - Firth AE, Michel AM, Choudhury KR, Ingolia NT, Atkins JF, Baranov PV (2012)
Observation of dually decoded regions of the human genome using ribosome profiling data.
Genome Research 22(11): 2219-2229 - Firth AE, Jagger BW, Wise HM, Nelson CC, Parsawar K, Wills NM, Napthine S, Taubenberger JK, Digard P, Atkins JF (2012)
Ribosomal frameshifting used in influenza A virus expression occurs within the sequence UCC_UUU_CGU and is in the +1 direction.
Open Biology 2 (10): 120109 - Fraser G, Prieto AI, Kahramanoglou C, Ali RM, Seshasayee ASN, Luscombe NM (2012)
Genomic analysis of DNA binding and gene regulation by homologous nucleoid-associated proteins IHF and HU in Escherichia coli K12.
Nucleic Acids Research 40(8): 3524-3537 - Fraser G, Kahramanoglou C, Prieto A, Khedkar S, Haase B, Gupta A, Benes V, Luscomb NM, Aswin ASN (2012)
Genomics of DNA cytosine methylation in Escherichia coli reveals its role in stationary phase transcription.
Nature communications 3: 886- - Ibrahim AEK, Arends MJ (2012)
Molecular typing of colorectal cancer: applications in diagnosis and treatment.
Diagnostic Histopathology 18(2): 70-80 - Ibrahim AEK, Cooke J, Zhang H, Greger L, Silva A-L, Massey D, Dawson C, Metz A, Parkes M (2012)
Mucosal genome-wide methylation changes in inflammatory bowel disease.
Inflammatory Bowel Diseases 18(11): 2128-2137 - Kelly AP, Jahnke M, Trowsdale J (2012)
Structural requirements for recognition of major histocompatibility complex class II by membrane-associated RING-CH (MARCH) protein E3 ligases.
Journal of Biological Chemistry 287(34): 28779-28789 - Kelly AP, Jahnke M, Trowsdale J (2012)
Uniquitination of human leukocyte antigen (HLA)-DM by different membrane-associated RING-CH (MARCH) protein family E3 ligases targets different endocytic pathways.
Journal of Biological Chemistry 287 (10): 7256-7264 - Koronakis V, Bulmer DM, Kharraz L, Grant AJ, Dean P, Morgan FJE, Michail H and others (2012)
The bacterial cytoskeleton modulates motility type 3 secretion and colonization in Salmonella.
PLoS Pathogens 8(1): e1002500 - Koronakis V, Humphreys D, Davidson A, Hume PJ (2012)
Salmonella virulence effector SopE and host GEF ARNO cooperate to recruit and activate WAVE to trigger bacterial invasion.
Cell Host & Microbe 11: 129-139 - Kouzarides T, Ougland R, Lando D, Jonson I, Dahl JA, Moen MN, Nordstrand LM, Rognes T, Lee JT, Klungland A, Larsen E (2012)
ALKBH1 is a histone H2A dioxygenase involved in neural differentiation.
Stem Cells 30: 2672-2682 - Kouzarides T, Dawson MA (2012)
Cancer epigenetics: from mechanism to therapy.
Cell 150:12-27 - Kouzarides T, Xhemalce B, Robson SC (2012)
Human RNA methyltransferase BCDIN3D regulates microRNA processing.
Cell 151: 278-288 - Kouzarides T, Watson AA, Mahajan P, Mertens HDT, Deery MJ, Zhang W, Pham P, Du X, Bartke T, Zhang W, Edlich C, Berridge G, Chen Y, Burgess-Brown NA, Wiechens N and others (2012)
The PHD and chromo domains regulate the ATPase activity of the human chromatin remodeler CHD4
Journal of Molecular Biology 422: 3-17 - Kouzarides T, Lando D, Balmer J, Laue ED (2012)
The S. pombe histone H2A dioxygenase Ofd2 regulates gene expression during hypoxia.
PLoS One 7(1): e29765 - Kouzarides T, Dawson MA, Huntly BJP (2012)
Targeting epigenetic readers in cancer.
New England Journal of Medicine 367(7): 647-657 - Kouzarides T, Dawson MA, Foster SD, Bannister AJ, Robson SC, Hannah R, Wang X, Xhemalce B and others (2012)
Three distinct patterns of histone H3Y41 phosphorylation mark active genes.
Cell Reports 2: 470-477 - Laman H, Gooding M, Tudzarova S, Worthington RJ and others (2012)
Exploring the interaction between siRNA and the sMoC biomolecule transporters: implications for small molecule-mediated delivery of siRNA.
Chemical Biology and Drug Design 79: 9-21 - Laman H, Kuiken HJ, Egan DA, Bernards R, Beijersbergen RL, Dirac AM (2012)
Identification of F-box only protein as a negative regulator of NF-kappaB signalling.
Journal of Cellular and Molecular Medicine 16(9): 2140-2149 - Moffett A, Male V, Gardner L (2012)
Isolation of cells from the feto-maternal interface.
Current Protocols in Immunology 97:7:40: 1-7 - Richards AJ, Nagendran S, McNinch A, Sandford RN, Snead MP (2012)
Somatic mosaicism and the phenotypic expression of COL2A1 mutations.
American Journal of Medical Genetics 158A(5): 1204-120
Richards AJ, McNinch A, Whittaker J, Treacy B, Oakhill K, Poulson A, Snead MP (2012)
Splicing analysis of unclassified variants in COL2A1 and COL11A1 identifies deep intronic pathogenic mutations.
European Journal of Human Genetics 20: 552-558 - Rudd CE, Lu Y, Schneider H (2012)
Murine regulatory T cells differ from conventional T cells in resisting the CTLA-4 reversal of TCR stop-signal.
Blood 120(23): 4560-4570 - Rudd CE, Jarvis GE, Bihan D, Hamaia S, Pugh N, Chevaert CJG, Pearce AC, Hughes CE, Watson SP, Ware J, Farndale RW (2012)
A role for adhesion and degranulated-promoting adapter protein in collagen-induced platelet activation mediated via integrin α2β1.
Journal of Thrombosis and Haemostasis 10(2): 268-277 - Sargent CA, Quilter CR, Bagga M, Moinie A, Junaid F (2012)
Gene structure and expression of serotonin receptor HTR2C in hypothalamic samples from infanticide and control sows.
BMC Neuroscience 2012: 13:37 - Smith GL, Hollinshead M, Johns HL, Sayers CL, Gonzalez-Lopez C, Elliott G (2012)
Endocytic tubules regulated by Rab GTPases 5 and 11 are used for envelopment of herpes simplex virus.
The Embo Journal 31(21): 4204-4220 - Smith GL, Doceul V, Hollingshead M (2012)
Le virus de la vaccine, un virus qui se propage plus vite qu’il ne se réplique.
(Vaccina virus, a virus that spreads faster than it replicates)
Virologie 16(2): 119-121 - Smith GL, Doceul V, Hollingshead M, Breiman A, Laval K (2012)
Protein B5 is required on extracellular enveloped vaccine virus for repulsion of superinfecting virions.
Journal of General Virology 93: 1876-1886 - Smith GL, Carrara G, Saraiva N, Gubser C, Johnson BF (2012)
Six-transmembrane topology for Golgi anti-apoptotic protein (GAAP) and Bax inhibitor 1 (B1-1) provides model for the transmembrane Bax inhibitor-containing motif (TMBIM) family.
Journal of Biological Chemistry 287(19): 15896-15905 - Smith GL, Ember SWJ, Ren H, Ferguson BJ (2012)
Vaccinia virus protein C4 inhibits NF-κB activation and promotes virus virulence.
Journal of General Virology 93: 2098-2108 - Stanley MA (2012)
Epithelial cell responses to infection with human papillomavirus.
Clinical Microbiology Reviews 25(2): 681-691 - Stanley MA (2012)
Genital human papillomavirus infections: current and prospective therapies.
Journal of General Virology 93: 681-691 - Stanley MA, Pinto LA, Trimble C (2012)
Human papillomavirus vaccines – immune responses.
Vaccine 30S: F83-F87 - Stanley MA, Winder DM, Sterling JC, Goon PKC (2012)
HPV infection, anal intra-epithelial neoplasia (AIN) and anal cancer: current issues.
BMC Cancer 12: 398 - Stanley MA (2012)
Vaccinate boys too.
Nature 488(7413): S10 - Stevenson PG, Lete C, Machiels B, Vanderplasschen A, Gillet L (2012)
Bovine herpesvirus type 4 glycoprotein L is nonessential for infectivity but triggers virion endocytosis during entry.
Journal of Virology 86(5): 2653-2664 - Stevenson PG, Milho R, Frederico B, Efstathiou S (2012)
A heparin-dependent herpesvirus targets the olfactory neuroepithelium for host entry.
PLOS Pathogens 8(11): e1002986 - Stevenson PG, Glauser DL, Kratz A-S (2012)
Herpesvirus glycoproteins undergo multiple antigenic changes before membrane fusion.
PLoS ONE 7(1): e30152 - Stevenson PG, Frederico B, Milho R, May JS, Gillet L (2012)
Myeloid infection links epithelial and B cell tropisms of murid herpesvirus-4.
PLOS Pathogens 8(9): 31002935 - Stevenson PG, Glauser DL, Gillet L (2013)
Virion endocytosis is a major target for murid herpesvirus-4 neutralization.
Journal of General Virology 93(6): 1316-1327 - Trowsdale J, Hogan L, Bhuju S, Jones DC, Laing K, Butcher P, Singh M, Vordermeier M, Allen RL (2012)
Characterisation of bovine leukocyte Ig-like receptors.
PLoS ONE 7(4): e34291 - Trowsdale J, Wines BD, Trist HM, Farrugia W, Ngo C, Areschoug T, Lindahl G, Fraser JD, Ramsland PA (2012)
A conserved host and pathogen recognition site on immunoglobulins: Structural and functional aspects.
Advances in Experimental Medicine and Biology 946: 87-112 - Trowsdale J, Jiang W, Johnson C, Jayaraman J, Simecek N, Noble J, Moffatt MF, Cookson WO, Traherne JA (2012)
Copy number variation leads to considerable diversity for B but not A haplotypes of the human KIR genes encoding NK cell receptors.
Genome Research 22: 1845-1854 - Trowsdale J, Ammann JU, Jahnke M, Dyson MR, Kaufman J (2012)
Detection of weak receptor-ligand interactions using IgM and J-chain-based fusion proteins.
European Journal of Immunology 42: 1354-1356 - Trowsdale J, Ormiston ML, Chang C, Long LL, Soon E, Jones D, Machado R, Treacy C, Toshner MR, Campbell K, Riding A, Southwood M, Pepke-Zaba J, Exley A, Trembath RC, Colucci F, Wills M, Morrell NW (2012)
Impaired natural killer cell phenotype and function in idiopathic and heritable pulmonary arterial hypertension.
Circulation 126(9): 1099-1109 - Trowsdale J, Bergen J van (2012)
Ligand specificity of killer cell immunoglobulin-like receptors: a brief history of KIR.
Frontiers in Immunology 3: Article 394 - Trowsdale J, Kruijf EM de, Sajet A, Nes JGH van, Putter H, Smit VTHBM, Eagle RA, Jafferji I, Liefers GJ, Velde CJH van de, Kuppen PJK (2012)
NKG2D ligand tumor expression and association with clinical outcome in early breast cancer patients: an observational study.
BMC Cancer 12: 24 - Trowsdale J, Qutob N, Balloux F, Raj T, Liu H, Procé SM de, Manika A (2012)
Signatures of historical demography and pathogen richness on MHC class I genes.
Immunogenetics 64: 165-175 - Turner SD, Laimer D, Dolznig H, Kollmann K, Vesely PW, Schlederer M, Merkel O, Kenner L and others (2012)
PDGFR blockade is a rational and effective therapy for NPM-ALK-driven lymphomas.
Nature Medicine 18(11): 1699-1704 - Watson CJ, Davidenko N, Gibb T, Schuster C, Best SM, Campbell JJ, Cameron RE (2012)
Biomimetic collagen scaffolds with anisotropic pore architecture.
Acta Biomaterialia 8: 667-676 - Watson CJ, Hughes K, Wickenden JA, Allen JE (2012)
Conditional deletion of Stat3 in mammary epithelium impairs the acute phase response and modulates immune cell numbers during post-lactational regression.
Journal of Pathology 227: 106-117 - Watson CJ, Caffarel MM, Zaragoza R, Pensa S, Li J, Green AR (2012)
Constitutive activation of JAK2 in mammary epithelium elevates Stat5 signaling, promotes alveologenesis and resistance to cell death and contributes to tumourigenesis.
Cell Death and Differentiation 19: 511-522 - Watson CJ, Smalley MJ, Kendrick H, Sheridan JM, Regan JL, Stingl J and others (2012)
Isolation of mouse mammary epithelial subpopulations: A comparison of leading methods.
Journal of Mammary Gland Biology and Neoplasia 17(2): 91-97 - Watson CJ, Kreuzaler P (2012)
Killing a cancer: what are the alternatives?
Nature Reviews Cancer 12(6): 411-424 - Watson CJ, Oliver CH, Khaled WT, Frend H, Nichols J (2012)
The Stat6-regulated KRAB domain zinc finger protein Zfp157 regulates the balance of lineages in mammary glands and compensates for loss of Gata-3.
Genes and Development 26(10): 1086-1097
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