Professor John Trowsdale
Key publications
- Copy number variation leads to diversity for B but not A haplotypes of the human KIR genes encoding NK cell receptors. Jiang W, Johnson, C, Jayaraman, J, Trowsdale, J, Traherne, JA. Genome Research 2012 in press
- OSCAR is a collagen receptor that costimulates osteoclastogenesis in DAP12-deficient humans and mice. Barrow AD, Raynal N, Andersen TL, Slatter DA, Bihan D, Pugh N, Cella M, Kim T, Rho J, Negishi-Koga T, Delaisse JM, Takayanagi H, Lorenzo J, Colonna M, Farndale RW, Choi Y, Trowsdale J. J Clin Invest. 2011 Sep;121(9):3505-16.
- BTN1A1, the mammary gland butyrophilin, and BTN2A2 are both inhibitors of T cell activation. Smith IA, Knezevic BR, Ammann JU, Rhodes DA, Aw D, Palmer DB, Mather IH, Trowsdale J. J Immunol. 2010 Apr 1;184(7):3514-25.
- Mechanisms of copy number variation and hybrid gene formation in the KIR immune gene complex. Traherne JA, Martin M, Ward R, Ohashi M, Pellett F, Gladman D, Middleton D, Carrington M, Trowsdale J. Hum Mol Genet. 2010 Mar 1;19(5):737-51.
- Ubiquitination of lysine-331 by Kaposi's sarcoma-associated herpesvirus protein K5 targets HFE for lysosomal degradation. Rhodes DA, Boyle LH, Boname JM, Lehner PJ, Trowsdale J. Proc Natl Acad Sci U S A. 2010 107:16240-5.