Dr Heike Laman
Key publications
- M. Lomonosov, E. K. Meziane, H. Ye, D. E. Nelson , S. J. Randle and H. Laman. 2011. Expression of Fbxo7 in haematopoietic progenitor cells cooperates with p53 loss to promote lymphomagenesis. PLoS One. In press.
- E. K. Meziane*, S. J. Randle*, D. E. Nelson, M. Lomonosov, H. Laman. 2011. Knockdown of Fbxo7 reveals its negative regulatory role in the proliferation and differentiation of B cells. J Cell Sci. 124(13):2175-2186. [Jun 9 Epub ahead of print] *Equal authorship.
- D. E. Nelson, and H. Laman. 2011. A competitive binding mechanism between Skp1 and Exportin (CRM1) controls the localisation of a subset of F-box proteins. J Biol Chem. 286(22):19804-15. [Mar 4 Epub ahead of print].
- R. J. Kirk, H. Laman*, P. P. Knowles, J. Murray-Rust, M. Lomonosov, E. K. Meziane and N. Q. McDonald*. 2008. Structure of a conserved dimerisation domain within Fbxo7 and PI31 links an E3 ubiquitin ligase and immunoproteasome regulation. J Biol Chem. 283(32):22325-35. *Co-corresponding author.
- H. Laman*, J. M. Funes, H. Ye, S. Henderson, L. Galienas-Garcia, E. Hara, P. Knowles, N.Q. McDonald and C. Boshoff. 2005. Transformation by Fbxo7 through selective assembly of cyclin D/cdk6 complexes. EMBO J. 24(17):3104-3116. *Corresponding author.