Dr Ian Brierley
Key publications
- Namy, O., Moran, S. J., Stuart, D. I., Gilbert, R. J. C. and Brierley I. (2006). A mechanical explanation of RNA pseudoknot function in programmed ribosomal frameshifting. Nature, 441, 244-247.
- Girnary, R., King, L., Robinson, L., Elston, R. and Brierley, I. (2007). Structure-function analysis of the ribosomal frameshifting signal of two HIV-1 isolates with increased resistance to viral protease inhibitors. J. Gen. Virol. 88, 226-235.
- Pennell, S., Manktelow, E., Flatt, A., Kelly, G., Smerdon, S. J. and Brierley, I. (2008). The stimulatory RNA of the Visna-Maedi retrovirus ribosomal frameshifting signal is an unusual pseudoknot with an inter-stem element. RNA 14, 1366-1377
- Powell, M. L., Napthine, S., Jackson, R. J., Brierley, I. and Brown T. D. K. (2008). Characterization of the termination-reinitiation strategy employed in the expression of influenza B virus BM2 protein. RNA, 14, 2394-2406.
- Flanagan, J. F., Namy, O., Brierley, I. and Gilbert, R. J. C. (2010). Direct observation of distinct A/P hybrid-state tRNAs in translocating ribosomes. Structure 18, 257-264.