Dr Mark Arends
Key publications
- Prognostic relevance of DNA copy number changes in colorectal cancer. Poulogiannis G, Ichimura K, Hamoudi R, Luo F, Leung SY, Yuen ST, Harrison DJ, Wyllie AH, Arends MJ. Journal of Pathology 2010; 220: 338 - 347.
- PARK2 deletions occur frequently in sporadic colorectal cancer and accelerate adenoma development in Apc mutant mice. Poulogiannis G, McIntyre R, Dimitriadi M, Apps JR, Wilson C, Ichimura K, Luo F, Cantley LC, Wyllie AH, Adams DJ, Arends MJ. Proc Natl Acad Sci U. S. A. 2010; 107(34):15145-15150.
- Mutant K-ras promotes carcinogen-induced murine colorectal tumourigenesis, but does not alter tumour chromosome stability. Luo F, Poulogiannis G, Ye H, Hamoudi R, Zhang W, Dong G, Arends MJ. Journal of Pathology 2011; 223: 390-399.
- Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi Anaemia. Crossan G, van der Weyden L, Rosado IV, Langevin F, Gaillard PH, McIntyre RE, Sanger Mouse Genetics Project, Gallagher F, Kettunen MI, Lewis DY, Brindle K, Arends MJ, Adams DJ, Patel KJ. Nature Genetics 2011; 43: 147-152.
- Mutant Nucleophosmin and cooperating pathways drive leukaemia initiation and progression in mice. Vassiliou GS, Cooper JL, Rad R, Li J, Rice S, Uren A, Rad L, Ellis P, Andrews R, Banerjee R, Grove C, Wang W, Liu P, Wright P, Arends MJ, Bradley A. Nature Genetics 2011: 43 (5) 470-475.