News and Events
Cambridge children's doctor scoops prestigious prize for cancer research to improve patient outcomes
Dr Matthew Murray has been chosen as the SPARKS Young Investigator of the Year 2012, thanks to his studies into malignant germ cell tumours.
A new aspect of host cell invasion by the Salmonella pathogen
Prof Vassilis Koronakis' team have uncovered a new path by which the bacterial pathogen Salmonella triggers its uptake into intestinal cells to initiate infection. They reveal this week in Cell Host & Microbe that pathogen and host guanine nucleotide exchange factors (GEFs) cooperate to control host cell WAVE complex regulation and pathogen macropinocytosis (picture shows Salmonella (red) engulfed by macropinosome).
Exposure to micronutrients prior to pregnancy has been associated with gene modifications in offspring
Prof Nabeel Affara is lead author of the study that finds that micronutrients affect methylation, which has been associated with changes in the immune system.
High-throughput decoding of anti-trypanosomal drug efficacy and resistance
Prof Mark C. Field, part of a collaborative study with investigators at the LSHTM and Sanger Institute, makes an important advance in the understanding of drug action in African trypanosomes.
Inhibition of apoptosis and NF-κB activation by vaccinia protein N1 occur via distinct binding surfaces and make different contributions to virulence
Dr Carlos Maluquer de Motes and Prof Geoffrey Smith have collaborative paper published in PLoS Pathogens.
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