An international collaboration lead by Dr Heather Griffin and Dr John Doorbar in the Department of Pathology, has lead to the development of a dual biomarker system for the molecular stratification of cervical neoplasia.
The combined detection of the human papillomavirus E4 antigen (green) along with the cellular p16 protein (brown) that is triggered by the viral E6/E7 genes overcomes many of the problems associated with conventional pathology approaches. The system is currently being developed into a diagnostic kit as a collaboration with Delft Diagnostic Laboratories in the Netherlands. The work is a Featured Article in the July edition of Modern Pathology
Cover Feature at http://www.nature.com/modpathol/index.html