skip to primary navigationskip to content
 

Dr Liz Hook

Lead Teacher Clinical Pathology

Senior Examiner in Clinical Pathology

Honorary Consultant Paediatric Histopathologist

Division of Cellular and Molecular Pathology

Medical Education

Germ Cell Tumour Histopathology


Biography:

I hold overall responsibilty for the organisation, delivery and examination of the Clinical Pathology Course.  As well as being Senior Examiner for Pathology for Years 4, 5 and 6 of the Cambridge Medical Course, I also lead on the Year 5 written assessments for the Final MB Part II.  I have a significant interest in medical education, in particular in the use of learning technology to enhance pathology learning.

I provide clinical sessions in paediatric pathology at CUHNHSFT.  My particular fields of interest are solid and haematological paediatric neoplasms.  I have a special interest in paediatric germ cell tumours and I am the lead Pathologist on the NCRI Paediatric Germ Cell Tumour Panel. 

Research Interests

Paediatric Germ Cell Tumours

Paediatric Lymphoma

Research Supervision

Much of my work is based around medical education in pathology and I am very happy to support and supervise student projects in this area.

Key Publications

Lymphoreticular Pathology

Anaplastic large cell lymphoma arises in thymocytes and requires transient TCR expression for thymic egress.

Malcolm TI, Villarese P, Fairbairn CJ, Lamant L, Trinquand A, Hook CE, Burke GA, Brugières L, Hughes K, Payet D, Merkel O, Schiefer AI, Ashankyty I, Mian S, Wasik M, Turner M, Kenner L, Asnafi V, Macintyre E, Turner SD.

Nat Commun. 2016 Jan 12;7:10087. doi: 10.1038/ncomms10087.

PMID:
26753883

Cold antibody autoimmune haemolytic anaemia in a child with diffuse large B cell lymphoma.

Uzunova L, Hook CE, Gattens M, Burke GA.

Ann Hematol. 2016 Jan;95(1):151-2. doi: 10.1007/s00277-015-2498-5. No abstract available.

PMID:
26365160

Anaplastic large cell lymphoma-propagating cells are detectable by side population analysis and possess an expression profile reflective of a primitive origin.

Moti N, Malcolm T, Hamoudi R, Mian S, Garland G, Hook CE, Burke GA, Wasik MA, Merkel O, Kenner L, Laurenti E, Dick JE, Turner SD.

Oncogene. 2015 Apr 2;34(14):1843-52. doi: 10.1038/onc.2014.112.

PMID:
24814516

Placental Pathology

Funisitis is associated with adverse neonatal outcome in low-risk unselected deliveries at or near term.

Jessop FA, Lees CC, Pathak S, Hook CE, Sebire NJ.

Virchows Arch. 2016 Apr;468(4):503-7. doi: 10.1007/s00428-015-1899-0.

PMID:
26868144

Umbilical cord coiling: clinical outcomes in an unselected population and systematic review.

Jessop FA, Lees CC, Pathak S, Hook CE, Sebire NJ.

Virchows Arch. 2014 Jan;464(1):105-12. doi: 10.1007/s00428-013-1513-2. Review.

PMID:
24259031